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Effects and Mechanisms of Action of Preussin, a Marine Fungal Metabolite, again...

Seabra, R; Malhão, F; Correia, A; Costa, C; Kijjoa, A; Rocha, E

Triple-negative breast cancer (TNBC) represents an aggressive subtype of breast cancer (BC) with a typically poorer prognosis than other subtypes of BC and limited therapeutic options. Therefore, new drugs would be particularly welcome to help treat TNBC. Preussin, isolated from the marine sponge-associated fungus, Aspergillus candidus, has shown the potential to reduce cell viability and proliferation as well ...


Trends in drowning mortality in Portugal from 1992 to 2019: comparing Global Bu...

Queiroga, AC; Seabra, R; Franklin, RC; Peden, AE

Introduction Imprecise data systems hinder understanding of drowning burden, even in high-income countries like Portugal, that have a well-implemented death certificate system. Consequently, national studies on drowning mortality are scarce. We aimed to explore drowning mortality in Portugal using national data and to compare these to Global Burden of Disease (GBD) estimates. Methods Data were obtained from the...


Trends in drowning mortality in Portugal from 1992 to 2019: comparing Global Bu...

Queiroga, AC; Seabra, R; Franklin, RC; Peden, AE

Introduction Imprecise data systems hinder understanding of drowning burden, even in high-income countries like Portugal, that have a well-implemented death certificate system. Consequently, national studies on drowning mortality are scarce. We aimed to explore drowning mortality in Portugal using national data and to compare these to Global Burden of Disease (GBD) estimates. Methods Data were obtained from the...


Digital Versus Conventional Rehabilitation After Total Hip Arthroplasty: A Sing...

Dias Correia, F; Nogueira, A; Magalhães, I; Guimarães, J; Moreira, M; Barradas, I; Molinos, M; Teixeira, L; Pires, J; Seabra, R; Lains, J; Bento, V

Background: The demand for total hip arthroplasty (THA) is rising. In the face of rapidly increasing health care costs, ensuring widespread, cost-effective rehabilitation is a priority. Technologies allowing independent home-based rehabilitation may be the key to facilitate access, improve effectiveness, and lower costs of care. Objective: The aim of this study was to assess the feasibility of a novel artificia...


Home-based Rehabilitation With A Novel Digital Biofeedback System versus Conven...

Correia, FD; Nogueira, A; Magalhães, I; Guimarães, J; Moreira, M; Barradas, I; Teixeira, L; Tulha, J; Seabra, R; Lains, J; Bento, V

In-person home-based rehabilitation and telerehabilitation can be as effective as clinic-based rehabilitation after total knee arthroplasty (TKA), but require heavy logistics and are highly dependent on human supervision. New technologies that allow independent home-based rehabilitation without constant human supervision may help solve this problem. This was a single-center, feasibility study comparing a digita...


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