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A Hydrophilic Sulfated Resveratrol Derivative for Topical Application: Sensitiz...
Jesus, Ana; Sebastião, Ana I.; Brites, Gonçalo; Correia-da-Silva, Marta; Cidade, Honorina; Cruz, Maria T.; Sousa, Emília; Almeida, Isabel F.Resveratrol (RSV), a naturally occurring metabolite, is widely used in skincare products, but its hydrophobicity impairs its own incorporation into cosmetic formulations. RSV-GS is a synthetic hydrophilic sulfated glycosylated derivative inspired by marine natural products that present a lower cytotoxicity than RSV while exhibiting similar levels of bioactivity. Herein, we predict the skin sensitization potenti...
Date: 2023
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Origin: Estudo Geral - Universidade de Coimbra