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Phytochemicals as Potential Epidrugs in Type 2 Diabetes Mellitus
Ramírez-Alarcón, K; Victoriano, M; Mardones, L; Villagran, M; Al-Harrasi, A; Al-Rawahi, A; Martins, N; Sharifi-Rad, J; Martorell, MType 2 diabetes Mellitus (T2DM) prevalence has significantly increased worldwide in recent years due to population age, obesity, and modern sedentary lifestyles. The projections estimate that 439 million people will be diabetic in 2030. T2DM is characterized by an impaired ß-pancreatic cell function and insulin secretion, hyperglycemia and insulin resistance, and recently the epigenetic regulation of ß-pancreat...
Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Att...
Sharifi-Rad, J; Butnariu, M; Ezzat, SM; Adetunji, CO; Imran, M; Sobhani, SR; Tufail, T; Hosseinabadi, T; Ramírez-Alarcón, K; Martorell, M; Maroyi, AMushrooms have a significant role in human diet as functional food and as a nutraceutical resource. The combination of its umami flavor, protein, vitamins, minerals and carbohydrates has meant that mushrooms could be considered a cheap food source for a long time in many countries. Moreover, mushrooms contain an excellent variety of bioactive metabolites that can be successful in both prevention and treatment o...
Plant-derived bioactives in oral mucosal lesions: A key emphasis to Curcumin, L...
Salehi, B; Jornet, PL; López, EPF; Calina, D; Sharifi-Rad, M; Ramírez-Alarcón, K; Forman, K; Fernández, M; Martorell, M; Setzer, WN; Martins, NOral mucosal lesions have many etiologies, including viral or bacterial infections, local trauma or irritation, systemic disorders, and even excessive alcohol and tobacco consumption. Folk knowledge on medicinal plants and phytochemicals in the treatment of oral mucosal lesions has gained special attention among the scientific community. Thus, this review aims to provide a brief overview on the traditional know...