Made available in DSpace on 2022-04-28T19:47:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-28; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The Leishmania developmental cycle comprises three main life forms in two hosts, indicating that the parasite is continually challenged due to drastic environmental changes. The disruption of this cycle is critical for discovering new therap...
Leishmania major infection of resistant mice causes a self-limited lesion characterized by macrophage activation and a Th1 proinflammatory response. Atherosclerosis is an inflammatory disease involving hypercholesterolemia and macrophage activation. In this study, we evaluated the influence of L. major infection on the development of atherosclerosis using atherosclerosissusceptible apolipoprotein E-deficient (a...
Texto completo: acesso restrito. p. 799-806; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-11T13:54:32Z No. of bitstreams: 1 Luís Fábio da S. Batista.pdf: 276239 bytes, checksum: 4e9777b507a531756c6e08755b0b58e8 (MD5); Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-10-09T15:59:03Z (GMT) No. of bitstreams: 1 Luís Fábio da S. Batista.pdf: 276239 bytes, checksum: 4e9777b507...
Trypanosoma cruzi, the etiological agent of Chagas disease, is a polymorphic species. Evidence suggests that the majority of the T. cruzi populations isolated from afflicted humans, reservoir animals, or vectors are multiclonal. However, the extent and the complexity of multiclonality remain to be established, since aneuploidy cannot be excluded and current conventional cloning methods cannot identify all the r...