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Acetonitrile Adducts of Tranexamic Acid as Sensitive Ions for Quantification at...
Silva, Eduarda M P; Barreiros, Luisa; Fernandes, Sara R.; Sa, Paula; Prates Ramalho, João P.; Segundo, MarcelaThe quantitative analysis of pharmaceuticals in biomatrices by liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) is often hampered by adduct formation. The use of the molecular ion resulting from solvent adducts for quantification is uncommon, even if formed in high abundance. In this work, we propose the use of a protonated acetonitrile adduct for the quantitati...
Date: 2023
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Origin: Repositório Científico da Universidade de Évora