5 documents found, page 1 of 1
Real-World Effectiveness and Safety of Glecaprevir/Pibrentasvir for the Treatme...
Vera, José; Gomes, André; Póvoas, Diana; Seixas, Diana; Maltez, Fernando; Pedroto, Isabel; Maia, Luís; Mota, Margarida; Vieira, Maria JoãoIntroduction: Information about pan-genotypic treatments for hepatitis in Portugal is scarce. We aimed to evaluate the effectiveness and safety of glecaprevir plus pibrentasvir (GLE/PIB) treatment for hepatitis C virus (HCV) infection in real-world clinical practice.Methods: An observational prospective study was implemented in six hospitals with 121 adult HCV patients who initiated treatment with GLE/PIB betwe...
Dor e articulação do punho na artrite reumatoide: O impacto na capacidade funci...
Seixas, Diana; Farinha, Fátima; Fonte, Marcos Pacheco da; Laranjeira, Manuel; Rua, MaríliaEnquadramento: Artrite reumatoide (AR), doença autoimune, inflamatória e crónica. Caracteriza-se por poliartrite, dor crónica e dificuldade em mobilizar as articulações, que levam à incapacidade funcional dos doentes. Objetivos: Avaliar a influência da mobilidade articular do punho e da dor, na capacidade funcional de doentes com AR. Metodologia: Estudo quantitativo, descritivo e correlacional, constituído por ...
Clinical and epidemiological features of hospitalized and ambulatory patients w...
Caria, João; Pinto, Raquel; Leal, Ema; Almeida, Vasco; Cristóvão, Gonçalo; Gonçalves, Ana Catarina; Torres, Margarida; Santos, Maria BeatrizMonkeypox, a neglected and re-emergent zoonotic disease caused by monkeypox virus (MPXV) infection, has been endemic in Central and Western Africa for decades. More recently, an outbreak has spread to a global level, occurring in sites with no previous reported cases and being clustered among men who have sex with men, suggesting new modes of transmission. There is an urgent need for research for a better under...
Brucellar Spondylodiscitis: Case Series of the Last 25 Years
Lebre, Ana; Velez, Jorge; Seixas, Diana; Rabadão, Eduardo; Oliveira, Joaquim; Saraiva da Cunha, J.; Silvestre, A. MeliçoIntroduction: Brucellosis is an endemic zoonosis in Portugal. Brucellar spondylodiscitis is one of the most frequent focal manifestations which may cause severe sequelae despite appropriate therapy.Material and Methods: Retrospective study of patients with diagnosis of brucellar spondylodiscitis admitted to the Infectious Diseases Department of Centro Hospitalar e Universitário de Coimbra, over a 25-year period...
Acute Bacterial Meningitis as an Occupational Disease
Seixas, Diana; Lebre, Ana; Crespo, Pedro; Ferreira, Eugénia; Serra, José Eduardo; Saraiva da Cunha, José GabrielStreptococcus suis is a zoonotic pathogen with worldwide distribution, responsible for more than 700 human cases globally reported. This infection affects mostly men, exposed to pig or pork, which leads to its usual classification as an occupational disease. We report a case of acute bacterial meningitis in a 44 years old male. According to his past medical history, the patient had alcohol consumption and worke...