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The Impact of a Western Diet and Resistance Training in a Rat Model of Mammary ...

Silva, Jessica; Ferreira, Rita; Neuparth, Maria J.; Seixas, Fernanda; Ginja, Mário; Pires, Maria J.; Faustino-Rocha, Ana I.; Duarte, José Alberto

This study aimed to investigate the impact of a Western diet and resistance training on cardiac remodeling in a rat model of chemically induced mammary cancer. Fifty-six female Wistar rats were randomly assigned to one of eight experimental groups, evaluating the impact of Western and standard diets, exercise and sedentarism, and the induction of mammary cancer. Mammary cancer was induced via the intraperitonea...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Effects of Ladder-Climbing Exercise on Mammary Cancer: Data from a Chemically I...

Silva, Jessica; Azevedo, Tiago; Aires, Inês; Medeiros, Catarina; Neuparth, Maria J.; Seixas, Fernanda; Ferreira, Rita; Faustino-Rocha, Ana I.

Breast cancer remains a significant global health issue, affecting both humans and companion animals, particularly female dogs and cats, where mammary tumors are among the most common cancers. Strategies to minimize the impact of this disease on patients, pet owners, and veterinary medicine are essential. This study analyses the effects of resistance training on the development of chemically induced mammary can...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Interplay Between Western Diet and Mammary Cancer: Data from a Chemically-induc...

Silva, Jessica; Aires, Inês; Peixoto, Francisco P.; Neuparth, Maria João; Queiroga, Felisbina; Seixas, Fernanda; Ferreira, Rita; Faustino-Rocha, Ana

This study aimed to investigate the influence of Western diet on mammary cancer in Wistar female rats, focusing on systemic responses and tumor development. Materials and Methods: Twenty-eight Wistar female rats were acclimatized and divided into four experimental groups (n=7 each): Western diet (WD), Western diet with N-methyl-N-nitrosourea (MNU) administration (WD+MNU), standard diet (CTR), and standard diet ...

Date: 2024   |   Origin: Biblioteca Digital do IPB

The role of natural compounds in rat mammary cancer: the beneficial effects of ...

Azevedo, Tiago; Silva, Jessica; Peixoto, Francisco P.; Silvestre-Ferreira, Ana C.; Gama, Adelina; Seixas, Fernanda; Finimundy, Tiane C.; Barros, Lillian

Breast cancer is the most diagnosed cancer among women, and a leading cause of death worldwide. Santolina chamaecyparissus L. is a plant with multiple health benefits, including anticancer and anti-diabetic properties. This study aimed to assess the chemopreventive effects of S. chamaecyparissus aqueous extract (SCE) in an animal model of mammary cancer. A total of 28 four-week-old female Wistar rats were divid...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Neurological lesions in cervids: a study in Portugal

Pires, Maria A.; Macêdo, J.; Seixas, Fernanda; Gama, Adelina; Alves, Anabela; Pinto, Maria de Lurdes; Pires, Isabel; Matos, Ana Cristina; Figueira, Luis

Brain samples were collected within the project "CWD Risk in Portugal", profiOng the infecOous diseases epidemiological surveillance and screening of chronic wasOng disease (CWD) during cervids hunts. The literature on wild animals´ neuropathological lesions is scarse. This work aims to describe the neuropathological findings in samples collected in deer hunted in Portugal.


Commentary : do people really care less about their cats than about their dogs?...

Baptista, Catarina Jota; Seixas, Fernanda; Gonzalo-Orden, José M.; Oliveira, Paula A.


Editorial : wildlife health consequences from environmental pollution

Baptista, Catarina Jota; Seixas, Fernanda; Gonzalo-Orden, José M.; Oliveira, Paula A.


How to design a biomonitoring study : a practical guide for veterinary professi...

Baptista, Catarina Jota; Seixas, Fernanda; Gonzalo-Orden, José M.; Oliveira, Paula A.

Currently, veterinarians can see their daily practice and medical tasks as constant opportunities for passive surveillance of One Health threats, such as infectious zoonotic diseases and chemical pollution effects on living beings. The present study aimed to provide a practical guide to designing a biomonitoring study during veterinary clinical practice without time-consuming procedures or significant costs. Th...


Heavy metal and metalloid concentrations in red deer (Cervus elaphus) and their...

Baptista, Catarina Jota; Seixas, Fernanda; Gonzalo-Orden, José M.; Patinha, Carla; Pato, Pedro; Silva, Eduardo Ferreira da; Fernandes, Gilberto

The red deer is an ungulate and large game species. The contamination of the ecosystems by metal(loid)s may lead to the exposure of animals (as well as humans) through water and food resources. The direct contact of hunters and wild animal meat consumers with deer carcasses may be a potential contaminant source. This study aimed to determine the metal(loid)s’ concentrations in the liver and kidney of red deer f...


The first full study of heavy metal(loid)s in western-European hedgehogs (Erina...

Baptista, Catarina Jota; Seixas, Fernanda; Gonzalo-Orden, José M.; Patinha, Carla; Pato, Pedro; Silva, Eduardo Ferreira da; Casero, María; Brazio, Erica

The western-European hedgehog (Erinaceus europaeus) is an insectivore with a wide distribution in Portugal and a potential tool for biomonitoring relevant One Health hazards, including heavy metal(loid)s’ pollution. The aim of this study was to positively contribute to the current knowledge about the metal(loid) pollution in Portugal. Forty-six hedgehogs (from rescue centres; with known provenance) were necrops...


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