1 document found, page 1 of 1
Sort by
Issue Date
NIS expression in thyroid tumors, relation with prognosis clinicopathological a...
Tavares, C; Coelho, MJ; Eloy, C; Melo, M; Rocha, AG; Pestana, A; Batista, R; Ferreira, LB; Rios, E; Selmi-Ruby, S; Cavadas, B; Pereira, LThyroid cancer therapy is based on surgery followed by radioiodine treatment. The incorporation of radioiodine by cancer cells is mediated by sodium iodide symporter (NIS) (codified by the SLC5A5 gene), that is functional only when targeted to the cell membrane. We aimed to evaluate if NIS expression in thyroid primary tumors would be helpful in predicting tumor behavior, response to therapy and prognosis. NIS ...
Date: 2018
|
Origin: Repositório Aberto da Universidade do Porto