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Update on Atopic Dermatitis

Torres, T.; Ferreira, E.; Gonçalo, M.; Mendes-Bastos, P.; Selores, M.; Filipe, P.

With an increasing prevalence during the past decades, atopic dermatitis has become a global health issue. A literature search following a targeted approach was undertaken to perform this non-systematic review, which intends to provide an overview of the epidemiology, pathophysiology, clinical features, comorbidities, and current therapies for the treatment of atopic dermatitis. In sum, this is a heterogeneous ...



Ustekinumab in Real-Life Practice: Experience in 116 Patients with Moderate-To-...

Raposo, I.; Bettencourt, A.; Leite, L.; Selores, M.; T, Torres

Ustekinumab is a monoclonal antibody directed against the p40 subunit common to both IL-12 and IL-23 cytokines. Although the evidence of ustekinumab efficacy and safety in clinical trials is extensively recognized, data on its use in clinical practice is limited. Our objective is to report on the real-life experience of two Portuguese dermatology departments with ustekinumab in patients with moderate to severe ...


Adult blaschkolinear acquired inflammatory skin eruption (BLAISE) with simultan...

Raposo, I.; Mota, F.; Fernandes, I.; Canelhas, Á.; Selores, M.

Blaschkitis and lichen striatus are generally distinguished in the literature by the age of onset, lesion distribution, and histopathology. However, there is currently no clear consensus among authors about whether to consider blaschkitis and lichen striatus different clinical entities or a spectrum ofthe same disease. We present a case of adult BLAISE with features of both lichen striatus and blaschkitis, whic...


Adult blaschkolinear acquired inflammatory skin eruption (BLAISE) with simultan...

Raposo, I.; Mota, F.; Fernandes, I.; Canelhas, Á.; Selores, M.

Blaschkitis and lichen striatus are generally distinguished in the literature by the age of onset, lesion distribution, and histopathology. However, there is currently no clear consensus among authors about whether to consider blaschkitis and lichen striatus different clinical entities or a spectrum ofthe same disease. We present a case of adult BLAISE with features of both lichen striatus and blaschkitis, whic...


Biosimilar Agents for Psoriasis Treatment: The Perspective of Portuguese Patients

Azevedo, A.; Bettencourt, A.; Selores, M.; Torres, T.

INTRODUCTION: Biosimilars are highly similar copies of previously approved original biologic medicines. Their introduction on the market may yield cost reduction. The aim of this study was to evaluate the perspectives of psoriasis patients on biosimilar medications. MATERIALS AND METHODS: We conducted a 14 questions survey of psoriasis patients receiving biological therapy and followed-up in a dermatology depar...


Nasolabial flap - alternative uses for a classic but versatile technique

Mota, F.; Horta, M.; Caetano, M.; Costa, V.; Selores, M.

The nasolabial flap is one of the most ancient techniques used in orofacial surgery. The authors report two cases of patients with skin cancer treated surgically with variations of the classic nasolabial flap by transposition (bilateral and folded) that highlight the broad applicability of this technique.


Annular elastolytic giant cell granuloma: a "visible" diagnosis

Raposo, I.; Mota, F.; Lobo, I.; Brandão, J.; Selores, M.

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of undetermined cause, characterized by annular plaques with raised erythematous borders in sun-exposed skin. The typical histologic features are dermal infiltration by multinucleated giant cells, elastin degeneration, and elastophagocytosis. The authors describe a clinical case of AEGCG, which exhibited an excellent response ...


Infantile bullous pemphigoid with "string of pearls sign"

Raposo, I.; Machado, S.; Sampaio, R.; Selores, M.

Bullous pemphigoid (BP) is an immune mediated bullous disease that is manifested by urticarial plaques with superimposed subepidermal blisters and significant pruritus. It is generally found in the elderly, but is rare in the pediatric population. A 5-month-old girl previously diagnosed with hand-foot-mouth disease was examined in our dermatology department owing to vesicles and bullae, initially located to the...


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