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Pilomatrixoma Recurring As Giant Form

Tavares, AT; Neiva-Sousa, M; Semedo, C; Martins, M; Gomes, P

Pilomatrixoma is a benign skin tumor that originates from the hair matrix. It usually appears in children and young adults and is preferably in the head and neck region. It clinically presents as an asymptomatic firm, solitary subcutaneous mass of less than 3 cm. When located in the preauricular area, it is often misdiagnosed as benign or malignant parotids, skin tumors, or sebaceous cysts. Its treatment of cho...


Retrospective Study of 114 Free Flaps for Head and Neck Oncological Reconstruct...

Silva, A; Caixeirinho, P; Vilares, M; Semedo, C; Martins, M; Zagalo, C; Casal, D

Introduction: The Portuguese experience in microsurgical reconstruction of the head and neck after oncological surgery is scantly described. The primary aim of this study was to characterize the use of microvascular reconstruction after head and neck tumor resection in a Portuguese tertiary oncological centerMaterial and Methods: The authors retrospectively evaluated 114 microvascular free flap procedures perfo...


Pseudoaneurysm of the Facial Artery Territory in an Odontogenic Infection Setting

Lopes Oliveira, MJ; Semedo, C; Quintela, MJ; Fragata, I; Gonçalves Coelho, C; Valejo Coelho, P

A pseudoaneurysm of the facial artery is a rare event. It results from vessel wall disruption with blood tamponade from the surrounding tissues, and is usually caused by blunt facial trauma, with other etiologies rarely reported. We present two cases of a pseudoaneurysm in the facial artery territory in an odontogenic infection setting, highlighting the importance of computed tomography angiography for diagnosi...


Odontoameloblastoma: a Propósito de um Caso Clínico

Semedo, C; Nunes da Silva, L; Foreid, S; Gomes, B; Pratas, AC; Valejo Coelho, P

O odontoameloblastoma é um tumor odontogénico misto muito raro. Reportam-se 29 casos bem documentados na literatura inglesa consultada, dos quais apenas 5 têm envolvimento do segmento anterior da mandíbula. Um homem de 51 anos apresentava um tumor da região anterior da mandíbula, com tumefacção dura, difusa e indolor na região parassinfisária direita da mandíbula. Radiograficamente existia extensa lesão radiolu...


Actividade biológica de complexos proteína-polissacárido produzidos em culturas...

Caldeira, A T; Martins, M R; Candeias, MF; Salvador, Cátia; Heber, M; Semedo, C; Karmali, A; Arteiro, J M

Trametes versicolor é um fungo utilizado como fonte alimentar e com propriedades medicinais conhecidas [1,2]. Em trabalhos anteriores avaliámos a produtividade de complexos proteína-polissacárido intra e extracelular (IPS e EPS) em culturas de T. versicolor utilizando várias fontes de carbono. Concluímos ser esta produção máxima no 14º dia de cultura e ser o repiso de tomate a fonte de carbono mais eficaz na qu...


Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRK...

Brás, JM; Guerreiro, RJ; Morgadinho, A; Januário, C; Dias, M; Calado, A; Semedo, C; Oliveira, CR; Hardy, J; Singleton, A

BACKGROUND: Mutations in the genes PRKN and LRRK2 are the most frequent known genetic lesions among Parkinson's disease patients. We have previously reported that in the Portuguese population the LRRK2 c.6055G > A; p.G2019S mutation has one of the highest frequencies in Europe. METHODS: Here, we follow up on those results, screening not only LRRK2, but also PRKN, SNCA and PINK1 in a cohort of early-onset and la...


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