7 documents found, page 1 of 1
Comparative analysis of the bronchoalveolar microbiome in Portuguese patients w...
Seixas, S; Kolbe, AR; Gomes, S; Sucena, M; Sousa, C; Vaz Rodrigues, L; Teixeira, G; Pinto, P; Tavares de Abreu, T; Bárbara, C; Semedo, J; Mota, LThe lung is inhabited by a diverse microbiome that originates from the oropharynx by a mechanism of micro-aspiration. Its bacterial biomass is usually low; however, this condition shifts in lung cancer (LC), chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD). These chronic lung disorders (CLD) may coexist in the same patient as comorbidities and share common risk factors, among whi...
Is the proteome of bronchoalveolar lavage extracellular vesicles a marker of ad...
Carvalho, AS; Moraes, MCS; Na, CH; Fierro-Monti, I; Henriques, A; Zahedi, S; Bodo, C; Tranfield, EM; Sousa, AL; Farinho, A; Rodrigues, LV; Pinto, PAcellular bronchoalveolar lavage (BAL) proteomics can partially separate lung cancer from non-lung cancer patients based on principal component analysis and multivariate analysis. Furthermore, the variance in the proteomics data sets is correlated mainly with lung cancer status and, to a lesser extent, smoking status and gender. Despite these advances BAL small and large extracellular vehicles (EVs) proteomes r...
Profiling of lung microbiota discloses differences in adenocarcinoma and squamo...
Gomes, S; Cavadas, B; Ferreira, JC; Marques, PI; Monteiro, C; Sucena, M; Sousa, C; Rodrigues, LV; Teixeira, G; Pinto, P; Abreu, TT; Bárbara, CThe lung is a complex ecosystem of host cells and microbes often disrupted in pathological conditions. Although bacteria have been hypothesized as agents of carcinogenesis, little is known about microbiota profile of the most prevalent cancer subtypes: adenocarcinoma (ADC) and squamous cell carcinoma (SCC). To characterize lung cancer (LC) microbiota a first a screening was performed through a pooled sequencing...
Non-indigenous species in Portuguese coastal areas, coastal lagoons, estuaries ...
Chainho, P; Fernandes, A; Amorim, A; Ávila, SP; Canning-Clode, J; Castro, JJ; Costa, AC; Costa, JL; Cruz, T; Gollasch, S; Grazziotin-Soares, C; Melo, RTrends in abundance, temporal occurrence and spatial distribution of marine and brackish nonindigenous species (NIS) are part of the indicators to assess the compliance of Good Environmental Status in the European Marine Strategy Framework Directive (EU-MSFD). European-wide regional and national databases for NIS will be useful for the implementation of the EU-MSFD but there are still spatial gaps for some regi...
Respiratory Sound Assessment Toolkit (RSAT) – A auscultação do futuro!
Marques, Alda; Oliveira, Ana; Semedo, J; Machado, Ana Filipa; Moreira, J; Rodrigues, J; Jesus, Luís; Jácome, Cristina; Aparício, JSem resumo disponível.
Empiema Torácico. Revisão Baseada em Três Casos Clínicos
Murinello, A; Figueiredo, AM; Semedo, J; Damásio, H; Ribeiro, NC; Peres, HO derrame parapneumónico caracteriza-se pela necessidade de um processo invasivo para a sua resolução e o empiema pela presença de pus na cavidade pleural. Em ambos os casos, o diagnóstico por TAC e o tratamento precoces resultando em menores morbilidade e mortalidade. São indicação para um tratamento invasivo os derrames loculados, os que ocupam mais de 50% do tórax, os que revelam coloração por Gram e exame c...
Cardiac Angiosarcoma. A Review
Murinello, A; Mendonça, P; Abreu, A; Santos, AL; Roquette, J; Pinto, E; Alpendra, J; Semedo, J; Rodrigues, A; Cunha, D; Coelho, JF; Lourenço, SBased on a case of a patient with angiosarcoma (AS) of the right atrium with superior vena cava syndrome associated with urticaria and polyarthralgias, who died soon after surgery, the authors present a brief review of the subject of cardiac AS, an extremely rare pathology, usually diagnosed late due to its non-specific symptomatology. Several topics are discussed, including mechanisms of clinical manifestation...