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The coronavirus disease 2019 (Covid-19): Key emphasis on melatonin safety and t...

Ramos, E; López-Muñoz, F; Gil-Martín, E; Egea, J; Álvarez-Merz, I; Painuli, S; Semwal, P; Martins, N; Hernández-Guijo, JM; Romero, A

Viral infections constitute a tectonic convulsion in the normophysiology of the hosts. The current coronavirus disease 2019 (COVID-19) pandemic is not an exception, and therefore the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, like any other invading mi-crobe, enacts a generalized immune response once the virus contacts the body. Melatonin is a systemic dealer that does not overlook ...


Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism ...

Martins, N; Quispe, C; Kirkin, C; Senol, E; Zulug, A; Özçelik, B; Ademiluyi, AO; Oyeniran, OH; Semwal, P; Kumar, M; Sharopov, F; López, V; Les, F

Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, lute...


Myricetin bioactive effects: Moving from preclinical evidence to potential clin...

Taheri, Y; Suleria, HAR; Martins, N; Sytar, O; Beyatli, A; Yeskaliyeva, B; Seitimova, G; Salehi, B; Semwal, P; Painuli, S; Kumar, A; Azzini, E

Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricet...


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