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Peripheral neuropathy in ALS: phenotype association

Carvalho, Mamede; Gromicho, Marta; Andersen, Peter; Grosskreutz, Julian; Kuzma-Kozakiewicz, Magdalena; Petri, Susanne; Uysal, Hilmi; Pinto, Susana

Amyotrophic lateral sclerosis (ALS) is a rare and progressive neurodegenerative disease mainly affecting upper and lower motor neurons but also causing multisystem involvement, in particular, associated with cognitive changes. Minor sensory fibre dysfunction has been described in the past and confirmed in recent studies. In a multicentre study investigating a population of 88 patients with ALS, the ESTEEM group...


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