3 documents found, page 1 of 1
Ligand-Targeted Delivery of Photosensitizers for Cancer Treatment
Gierlich, Piotr; Mata, Ana I.; Donohoe, Claire; Brito, Rui M. M.; Senge, Mathias O.; Silva, Lígia C. Gomes daPhotodynamic therapy (PDT) is a promising cancer treatment which involves a photosensitizer (PS), light at a specific wavelength for PS activation and oxygen, which combine to elicit cell death. While the illumination required to activate a PS imparts a certain amount of selectivity to PDT treatments, poor tumor accumulation and cell internalization are still inherent properties of most intravenously administer...
Platinum(II) Ring-Fused Chlorins as Near-Infrared Emitting Oxygen Sensors and P...
Pereira, Nelson A. M.; Laranjo, Mafalda; Casalta-Lopes, João; Serra, Arménio C.; Piñeiro, Marta; Pina, João; Seixas de Melo, J. SérgioNovel near-infrared luminescent compounds based on platinum(II) 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-fused chlorins are described. These compounds have high photostability and display light emission, in particular simultaneous fluorescence and phosphorescence emission in solution at room temperature, in the biologically relevant 700-850 nm red and near-infrared (NIR) spectral region, making them excellent ...
Characterization of excited electronic states in free-base porphyrin molecules
Senge, Mathias O.