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Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism ...

Martins, N; Quispe, C; Kirkin, C; Senol, E; Zulug, A; Özçelik, B; Ademiluyi, AO; Oyeniran, OH; Semwal, P; Kumar, M; Sharopov, F; López, V; Les, F

Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, lute...


Diet, lifestyle and cardiovascular diseases: Linking pathophysiology to cardiop...

Sharifi-Rad, J; Rodrigues, CF; Sharopov, F; Docea, AO; Karaca, AC; Sharifi-Rad, M; Karincaoglu, DK; Gülseren, G; Senol, E; Demircan, E; Taheri, Y

Heart and blood vessels disorders comprise one of the main causes of death worldwide. Pharmacologically active natural compounds have been used as a complementary therapy in cardiovascular disease around the world in a traditional way. Dietary, natural bioactive compounds, as well as healthy lifestyles, are considered to prevent coronary artery diseases. Pre-clinical and clinical studies reported that consumpti...


Targeted Gene Panel Sequencing for Early-onset Inflammatory Bowel Disease and C...

Petersen, BS; August, D; Abt, R; Alddafari, M; Atarod, L; Baris, S; Bhavsar, H; Brinkert, F; Buchta, M; Bulashevska, A; Chee, R; Cordeiro, AI; Dara, N

Background: In contrast to adult-onset inflammatory bowel disease (IBD), where many genetic loci have been shown to be involved in complex disease etiology, early-onset IBD (eoIBD) and associated syndromes can sometimes present as monogenic conditions. As a result, the clinical phenotype and ideal disease management in these patients often differ from those in adult-onset IBD. However, due to high costs and the...


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