Introduction: Bone scintigraphy (BS) has emerged as a non-invasive technique of increasing importance in the diagnosis of transthyretin cardiac amyloidosis (CA). The most commonly used approaches include visual grading and semi-quantitative analysis. However, these techniques are limited by operator dependence and subjectivity in interpretation. To address these challenges, absolute quantification techniques ar...
Introdução – Os métodos de Inteligência Artificial (IA) como o deep learning (DL) e, em particular, as convolutional neural networks (CNN) caracterizam-se por executar tarefas que normalmente requerem cognição humana. Nos estudos de perfusão do miocárdio, os sistemas de IA têm assumido importância como ferramenta auxiliar aos especialistas de medicina nuclear, particularmente para classificação de imagem no âmb...
Introdução – Os métodos de Inteligência Artificial (IA) como o deep learning (DL) e, em particular, as convolutional neural networks (CNN) caracterizam-se por executar tarefas que normalmente requerem cognição humana. Nos estudos de perfusão do miocárdio, os sistemas de IA têm assumido importância como ferramenta auxiliar aos especialistas de medicina nuclear, particularmente para classificação de imagem no âmb...
Since the 19th century, the Lower Tejo River (western Iberia) provide extensive evidence of Neanderthal occupation. However, due to the absence of long-term, well-funded projects and of fully-equipped research facilities, we still do not have a clear framework for the Neanderthal occupation of this crucial territory. Nowadays, probably more than ever, the increasing impact of urbanization and intensive agricult...
Over the last decades, gold nanoparticles (AuNPs) have proven to be remarkable tools for drug delivery and theranostic applications in cancer treatment. On the other hand, Pt(IV) prodrugs have been employed as an interesting alternative to the more common Pt(II) complexes, such as cisplatin, for cancer chemotherapy. Searching to design an image-guided nanocarrier to deliver selectively Pt(IV) prodrugs to tumors...
Introduction – Multigated acquisition (MUGA) scan is mainly used for the assessment of left ventricular ejection fraction (LVEF) in patients who undergo cardiotoxic chemotherapy drugs. When applying automatic (A) or manual (M) processing methods, some biases in the quantitative metrics can be obtained. The aim of this study is to evaluate the influence of A and M methods, specifically, the inter and intraoperat...
Introduction – Myocardial Perfusion Imaging (MPI) by single-photon emission computed tomography (SPECT) is one of the most widely used Non-invasive imaging tests in the diagnosis of coronary artery disease that requires correct segmentation of the left ventricle (LV), to extract perfusion parameters. The aim of this study is to evaluate the influence of automatic (A) vs. manual (M) segmentation in the quantific...
Introduction – Brain perfusion imaging (BPI) is an imaging study that allows the acquisition of three-dimensional tomographic images of the biodistribution of a tracer, reflecting regional brain perfusion. Therefore, the color scale used has a major role in the clinical interpretation of these images. Aim – To study the influence of the color scales in qualitative evaluation of the BPI and to conclude which are...
In December 2019, a novel coronavirus was identified in Wuhan (China), from a cluster of patients with unexplained pneumonia and termed SARS-CoV-2, responsible for Coronavirus Disease (COVID)-19. Medical imaging modalities play an important role in the management of COVID-19 infection. Consequently, it is necessary to identify strategies and procedures for infection control in the medical imaging department. Th...
Introduction – The maximum standardized uptake value (SUVmax) determination in Positron Emission Tomography (PET) with [68Ga] Ga-DOTA-TATE, allows the quantification of the density of somatostatin receptors, overexpressed by Neuroendocrine Tumors (NET). Related to the physiological and pathological pattern, the SUVmax analysis complements the visual assessment, yet this differentiation is co...