IntroductionMillions of people have their health and social status impacted because of the harmful use of alcohol and drugs.1 ObjectiveTo evaluate the effectiveness of a training program for self-management for substance addiction consequences. MethodsAdults integrated in a minimum of 5 weeks on a medication-based programs for alcohol and other drugs were randomly selected on this pilot trial conducted in a sin...
Therapeutic interventions for people with problematic use of psychoactive substances can help tackle specific needs related to substance addiction consequences. This modified e-Delphi study aimed to establish consensus on a training program for self-management of substance addiction consequences. The study was conducted between February and April 2022, with an experts’ sample of 28 participants in the first rou...
Therapeutic interventions for people with problematic use of psychoactive substances can help tackle specific needs related to substance addiction consequences. This modified e-Delphi study aimed to establish consensus on a training program for self-management of substance addiction consequences. The study was conducted between February and April 2022, with an experts’ sample of 28 participants in the first rou...
Structured intervention programs are an important resource for supporting people with substance addiction. Although evidence suggests that they improve health outcomes, such as specifc symptoms, less is known about their impact on patients’ ability to self-manage the consequences of substance addiction. The aim of this review is to scope outpatient intervention programs focused on the self-management of substan...
The field of protein data mining has been growing rapidly in the last years. To characterize proteins and determine their function from their amino acid sequences are challenging and long-standing problems, where Bioinformatics and Machine Learning have an emergent role. A myriad of machine and deep learning algorithms have been applied in these tasks with exciting results. However, tools and platforms to calcu...
A challenging problem in Bioinformatics is to predict protein structure, properties, activities or interactions from their aminoacid sequences. Sequence-derived physicochemical features of proteins have been used to support the development of Machine Learning (ML) models. However, tools and platforms to calculate features from protein sequences and train ML models are scarce and have limitations in terms of per...
Viral fusion proteins are attached to the membrane of enveloped viruses (a group that includes Coronaviruses, Dengue, HIV and Influenza) and catalyze fusion between the viral and host membranes, enabling the virus to insert its genetic material into the host cell. Given the importance of these biomolecules, this work presents a centralized database containing the most relevant information on viral fusion protei...
The authors author would like to thank Fundação para a Ciência e Tecnologia (FCT) - Portugal the financial support for the PhD grants with references SFRH/BD/74263/2010 and SFRH/BD/87392/2012; Biometrics represents a return to a natural way of identification: testing someone by what (s)he is, instead of relying on something (s)he owns or knows seems likely to be the way forward. Biometric systems that include m...
No âmbito da unidade curricular Estágio de Integração à Vida Profissional do 4º ano do curso de Farmácia - 1º Ciclo do ano letivo de 2017/2018, da Escola Superior de Saúde do Instituto Politécnico da Guarda, foram realizados dois estágios em diferentes áreas: Farmácia Comunitária e Farmácia Hospitalar, totalizando 840 horas. O estágio em Farmácia Comunitária foi realizado no 1º semestre, com início a 30 de outu...
Introdução: As reações de hipersensibilidade a fármacos podem limitar-se a um exantema cutâneo não específico, ou manifestar-se por um síndrome multissistémico, com prognóstico muito variável, como é o caso do síndrome DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms). Caso clínico: Os autores apresentam o caso clínico de uma menina admitida no Serviço de Urgência por um síndrome febril prolongado a...