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Phytochemicals and quaternary phosphonium ionic liquids: Connecting the dots to...

Chavarria, D; Anabela Borges; Benfeito, S; Sequeira, L; Ribeiro, M; Oliveira, C; Borges, F; Simões, M; Cagide, F; Simões M

Introduction: The infections by multidrug-resistant bacteria are a growing threat to human health, and the efficacy of the available antibiotics is gradually decreasing. As such, new antibiotic classes are urgently needed. Objectives: This study aims to evaluate the antimicrobial activity, safety and mechanism of action of phytochemical-based triphenylphosphonium (TPP') conjugates. Methods: A library of phytoch...


Juvenile Gout: Rare and Aggressive

Coelho Henriques, C; Monteiro, A; Lopéz, B; Sequeira, L; Panarra, A; Riso, N


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