3 documents found, page 1 of 1
Production and characterization of electrospun silk fibroin based asymmetric me...
Miguel, Sónia P.; Simões, Déborah; Moreira, André; Sequeira, Rosa Maria Saraiva; Correia, Ilídio Joaquim SobreiraNowadays, wound dressings with improved properties are under development and among them, asymmetric membranes have gained an increasing interest due to their two-layered structure that mimic both the epidermis and dermis layers of the skin. Herein, a new asymmetric membrane was produced using the electrospinning technique. The top layer was produced with silk fibroin (SF) and poly(caprolactone) to reproduce the...
Desenvolvimento de uma nova membrana bioativa para o tratamento de lesões da pele
Sequeira, Rosa Maria SaraivaThe skin is the outermost organ of the body and its acts as a protective barrier. Furthermore, skin is also responsible for the regulation of the body temperature and also for the maintenance of homeostasis. However, different types of injuries (burns, surgical interventions and/or chronic wounds), affect skin structure and functions. When a skin injury occurs, it is crucial to cover the wound site as soon as p...
Development of a poly(vinyl alcohol)/lysine electrospun membrane-based drug del...
Sequeira, Rosa Maria Saraiva; Miguel, Sónia; Cabral, Cátia S. D.; Moreira, André; Ferreira, Paula; Correia, I.J.Nanofiber-based wound dressings are currently being explored as delivery systems of different biomolecules for avoiding skin infections as well as improve/accelerate the healing process. In the present work, a nanofibrous membrane composed of poly(vinyl alcohol) (PVA) and lysine (Lys) was produced by using the electrospinning technique. Further, anti-inflammatory (ibuprofen (IBP)) and antibacterial (lavender oi...