15 documents found, page 1 of 2
Crosslinked poly(hydroxyurethane) films from biobased carbonates: Structure-pro...
Frias, Célia F.; Fonseca, Ana C.; Coelho, Jorge F. J.; Serra, ArménioIn this work, crosslinked poly(hydroxyurethane) (PHU) films were prepared by the reaction of biobased cyclic carbonates (BisCC), with different chain lengths, with hyperbranched poly(ethyleneimine) (PEI) under amenable conditions and in the absence of catalysts. Fourier transform infrared (FTIR) spectroscopy revealed that the carbonate groups were completely consumed in the crosslinking reaction and the gel con...
Photodegradable Non‐Drying Hydrogel Substrates for Liquid Metal Based Sustainab...
Fonseca, Rita G.; Hajalilou, Abdollah; Freitas, Marta; Kuster, Aline; Parvini, Elahe; Serra, Arménio; Coelho, Jorge; Tavakoli, MahmoudThe increasing interest in disposable electronics such as wearable patches, e-textiles, and smart packaging, warns emergence of another man-made disaster. A paradigm shift toward a more sustainable future through the development of soft material architectures that are robust and durable, but also degradable by external stimuli is proposed. Hydrogels, a class of soft polymers with exceptional properties, and hig...
Glycopolymers Mediate Suicide Gene Therapy in ASGPR-Expressing Hepatocellular C...
Santo, Daniela; Cordeiro, Rosemeyre A.; Mendonça, Patrícia V.; Serra, Arménio; Coelho, Jorge; Faneca, HenriqueCationic glycopolymers stand out as gene delivery nanosystems due to their inherent biocompatibility and high binding affinity to the asialoglycoprotein receptor (ASGPR), a target receptor overexpressed in hepatocellular carcinoma (HCC) cells. However, their synthesis procedure remains laborious and complex, with problems of solubilization and the need for protection/deprotection steps. Here, a mini-library of ...
Bioactive surfaces with well-defined amphiphilic copolymers containing a natura...
Pereira, Vanessa A.; Mendonça, Patrícia V.; Branco, Rita; Morais, Paula V.; Coelho, Jorge F. J.; Serra, ArménioNew amphiphilic cationic copolymers based on poly((methacryloyloxy) ethyl trimethylammonium chloride) (PMETAC) and bio-based poly(thymol methacrylate) (PTMA) were prepared by atom transfer radical polymerization (ATRP) methods, using low concentration of metal catalyst and a bio-based eutectic mixture (EM), composed of L-menthol and thymol. The antimicrobial activity of the polymers was evaluated against Gram-p...
Suppression of back electron recombination on the photoanode-electrolyte interf...
Rodrigues, Daniela F.S.L.; Martins, Jorge; SAUVAGE, Frédéric; Abreu, Carlos M.R.; Serra, Arménio; Ivanou, Dzmitry; Mendes, Adélio; Coelho, JorgeDye-sensitized solar cells (DSSC) are one of the most intensively developing PV technology to meet the emerging needs of wireless power for billions of IoT devices and wireless electronics; DSSCs have recently entered the indoor PV market. Suppressors of back electron recombination on the photoanode-electrolyte interface, also known as co-adsorbents, are key components of the DSSCs to obtain high power conversi...
Replacing Harmful Flame Retardants with Biodegradable Starch-Based Materials in...
Carvalho, Bárbara O.; Gonçalves, Luís P.C.; Mendonça, Patrícia V.; Pereira, João P.; Serra, ArménioThe addition of toxic flame retardants to commercially available polymers is often required for safety reasons due to the high flammability of these materials. In this work, the preparation and incorporation of efficient biodegradable starch-based flame retardants into a low-density polyethylene (LDPE) matrix was investigated. Thermoplastic starch was first obtained by plasticizing starch with glycerol/water or...
Calcium Phosphate Ceramics Can Prevent Bisphosphonate-Related Osteonecrosis of ...
Paulo, Siri; Laranjo, Mafalda; Paula, Anabela; Abrantes, Ana Margarida; Martins, João; Marto, Carlos Miguel; Coelho, Ana Sofia; Casalta-Lopes, JoãoBisphosphonate-associated osteonecrosis of the jaw (BRONJ), a post-surgical non-healing wound condition, is one of the most common side effects in patients treated with nitrogen-containing bisphosphonates. Its physiopathology has been related with suppression of bone turnover, of soft tissue healing and infection. Biphasic calcium phosphates (BCP) are used as a drug delivery vehicle and as a bone substitute in ...
Thiourea Dioxide As a Green and Affordable Reducing Agent for the ARGET ATRP of...
Mendonça, Patrícia V.; Ribeiro, Jessica P.M.; Abreu, Carlos M. R.; Guliashvili, Tamaz; Serra, Arménio; Coelho, JorgeThiourea dioxide, a green and inexpensive compound used at industrial scale, was employed as reducing agent for the controlled polymerization of a wide range of monomer families, namely, acrylates (methyl acrylate, 2-hydroxyethyl acrylate, butyl acrylate, methacrylates (2-(dimethylamino)ethyl methacrylate, 2-aminoethyl methacrylate hydrochloride, and methyl methacrylate), styrene, acrylonitrile, and vinyl chlor...
Higher activation barriers can lift exothermic rate restrictions in electron tr...
Mentel, Kamila K.; Serra, Arménio; Abreu, Paulo E.; Arnaut, Luís G.Electron transfer reactions are arguably the simplest chemical reactions but they have not yet ceased to intrigue chemists. Charge-separation and charge-recombination reactions are at the core of life-sustaining processes, molecular electronics and solar cells. Intramolecular electron donor-acceptor systems capture the essential features of these reactions and enable their fundamental understanding. Here, we re...
Recent Developments in Antimicrobial Polymers: A Review
Santos, Madson R. E.; Fonseca, Ana C.; Mendonça, Patrícia V.; Branco, Rita; Serra, Arménio; Morais, Paula V.; Coelho, Jorge F. J.Antimicrobial polymers represent a very promising class of therapeutics with unique characteristics for fighting microbial infections. As the classic antibiotics exhibit an increasingly low capacity to effectively act on microorganisms, new solutions must be developed. The importance of this class of materials emerged from the uncontrolled use of antibiotics, which led to the advent of multidrug-resistant micro...