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MicroRNAs (miRNAs) have emerged as crucial regulators of gene expression and have been implicated in various physiological and pathological processes, including cardiovascular diseases. The clinical presentation, diagnostic criteria, and proposed pathophysiological mechanisms of Takotsubo Syndrome (TTS) are discussed, with an emphasis on the emerging evidence implicating miRNAs in its etiology and progression. ...
Diastasis rectus abdominis is produced by an anormal separation of the rectus abdominis with s widening of the Linea alba, producing a deformity of the abdominal Wall when the abdomen is contracted. It can be symptomatic provoking pain or discomfort in the abdomen, musculoskeletal or urogenital problems and a negative corporal image with consequences in the quality of life. The most frequent presentations are i...
Intraoperative lesions of the recurrent laryngeal nerve (RLN) are rare, but have serious consequences. The authors present a new technique for repairing the RLN based on an experimental study using a vein-muscle graft between the tops of the RLN. The goal is to restore normal movements of the vocal cord. Nine animals were operated on, six in the nerve reconstruction group (NRG) and three in the control group (C...
Chronic venous disease (CVeD) is a prevalent condition with a significant socioeconomic burden, yet the pathophysiology is only just beginning to be understood. Previous studies concerning the dysregulation of matrix metalloproteinases (MMPs) and their inhibitors (tissue inhibitors of metalloproteinases (TIMPs)) within the varicose vein wall are inconsistent and disregard clinical progression. Moreover, it is h...