5 documents found, page 1 of 1

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Robotic Approach in the Treatment of Esophageal Cancer

Fraga, Ana Emília; Almeida, João; Serralheiro, Pedro; Bernardes, António; Tralhão, José Guilherme

.; .

Date: 2026   |   Origin: Revista Portuguesa de Cirurgia

MicroRNAs in takotsubo syndrome: a systematic review of regulatory networks in ...

Sousa, Domingos; Martins, Filipa Abreu; Luís, Ângelo; Serralheiro, Pedro

MicroRNAs (miRNAs) have emerged as crucial regulators of gene expression and have been implicated in various physiological and pathological processes, including cardiovascular diseases. The clinical presentation, diagnostic criteria, and proposed pathophysiological mechanisms of Takotsubo Syndrome (TTS) are discussed, with an emphasis on the emerging evidence implicating miRNAs in its etiology and progression. ...

Date: 2025   |   Origin: Repositório Científico IPVC

LAPAROSCOPIC REPAIR OF UMBILICAL HERNIA AND DIASTASIS RECTI BY LIRA TECHNIQUE

Maillo, Carmen; Serralheiro, Pedro; Piçarra, Genoveva; Oliveira, Maria de Jesús; Abreu, Raquel Camacho; Figueiredo, Nuno

Diastasis rectus abdominis is produced by an anormal separation of the rectus abdominis with s widening of the Linea alba, producing a deformity of the abdominal Wall when the abdomen is contracted. It can be symptomatic provoking pain or discomfort in the abdomen, musculoskeletal or urogenital problems and a negative corporal image with consequences in the quality of life. The most frequent presentations are i...

Date: 2024   |   Origin: Revista Portuguesa de Cirurgia

Repair of the recurrent laryngeal nerve: Experimental study.

Silveira, Luís; Antunes, Luis; Silva, Severiano; Ferreira, David; Soares, Salviano; Pinto, Maria; Lebre, Pedro; Dionísio, Isabel; Serralheiro, Pedro

Intraoperative lesions of the recurrent laryngeal nerve (RLN) are rare, but have serious consequences. The authors present a new technique for repairing the RLN based on an experimental study using a vein-muscle graft between the tops of the RLN. The goal is to restore normal movements of the vocal cord. Nine animals were operated on, six in the nerve reconstruction group (NRG) and three in the control group (C...


Variability of MMP/TIMP and TGF-β1 Receptors throughout the Clinical Progressio...

Serralheiro, Pedro; Novais, António; Cairrão, Elisa; Maia, Cláudio; Almeida, Carlos M. Costa; Verde, Ignacio

Chronic venous disease (CVeD) is a prevalent condition with a significant socioeconomic burden, yet the pathophysiology is only just beginning to be understood. Previous studies concerning the dysregulation of matrix metalloproteinases (MMPs) and their inhibitors (tissue inhibitors of metalloproteinases (TIMPs)) within the varicose vein wall are inconsistent and disregard clinical progression. Moreover, it is h...


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