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Bioguided Identification of Active Antimicrobial Compounds from Asphodelus bent...

Malmir, Maryam; Lima, Katelene; Camões, Sérgio Póvoas; Manageiro, Vera; Duarte, Maria Paula; Miranda, Joana Paiva; Serrano, Rita

Root tubers of Asphodelus bento-rainhae subsp. bento-rainhae (AbR), a vulnerable endemic species, and Asphodelus macrocarpus subsp. macrocarpus (AmR) have traditionally been used in Portugal to treat inflammatory and infectious skin disorders. The present study aims to evaluate the in vitro antimicrobial activity of crude 70% and 96% hydroethanolic extracts of both medicinal plants, specifically against multidr...


Identification of Marker Compounds and In Vitro Toxicity Evaluation of Two Port...

Malmir, Maryam; Lima, Katelene; Póvoas Camões, Sérgio; Manageiro, Vera; Duarte, Maria Paula; Paiva Miranda, Joana; Serrano, Rita

The leaves of Asphodelus bento-rainhae subsp. bento-rainhae, an endemic Portuguese species, and Asphodelus macrocarpus subsp. macrocarpus have been used as food, and traditionally as medicine, for treating ulcers, urinary tract, and inflammatory disorders. The present study aims to establish the phytochemical profile of the main secondary metabolites, together with the antimicrobial, antioxidant and toxicity as...


Monographic Quality Parameters and Genotoxicity Assessment of Asphodelus bento-...

Malmir, Maryam; Serrano, Rita; Lima, Katelene; Duarte, Maria Paula; Moreira da Silva, Isabel; Silva Lima, Beatriz; Caniça, Manuela; Silva, Olga

Root tubers of Asphodelus bento-rainhae subsp. bento-rainhae (AbR), an endemic species with relevant interest due to conservation concerns, and Asphodelus macrocarpus subsp. macrocarpus (AmR) have been traditionally used for culinary and medicinal purposes, mainly associated with skin infection and inflammation. The present study aims to establish the quality control criteria for the proper characterization of ...


Contribution to the Preclinical Safety Assessment of Lannea velutina and Sorind...

Malú, Quintino; Lima, Katelene; Malmir, Maryam; Pinto, Rui; da Silva, Isabel Moreira; Catarino, Luís; Duarte, Maria Paula; Serrano, Rita; Rocha, João

first_pagesettingsOrder Article Reprints Open AccessArticle Contribution to the Preclinical Safety Assessment of Lannea velutina and Sorindeia juglandifolia Leaves by Quintino Malú 1,Katelene Lima 1,Maryam Malmir 1,Rui Pinto 1,2,Isabel Moreira da Silva 1ORCID,Luís Catarino 3ORCID,Maria Paula Duarte 4,Rita Serrano 1ORCID,João Rocha 1ORCID,Beatriz Silva Lima 1 andOlga Silva 1,*ORCID 1 Research Institute for Medic...


A Comprehensive Review on the Medicinal Plants from the Genus Asphodelus

Malmir, Maryam; Serrano, Rita; Caniça, Manuela; Silva-Lima, Beatriz; Silva, Olga

Abstract: Plant-based systems continue to play an essential role in healthcare, and their use by different cultures has been extensively documented. Asphodelus L. (Asphodelaceae) is a genus of 18 species and of a total of 27 species, sub-species and varieties, distributed along the Mediterranean basin, and has been traditionally used for treating several diseases particularly associated with inflammatory and in...


Ciência, Crise e Mudança. 3.º Encontro Nacional de História das Ciências e da T...

Brandão, José Manuel; Nunes, Maria de Fátima; Dias, Pedro Sousa; Abrantes, Isabel; Almeida, Maria Antónia; Antunes, Carlos; Assis, José Luís

III Encontro Nacional de História das Ciências e da Tecnologia. O Centro de Estudos de História e Filosofia da Ciência, organiza o 3.º Encontro Nacional de História da Ciência e da Técnica, sob o tema «Ciência, Crise e Mudança» que tem lugar na Universidade de Évora, nos dias 26, 27 e 28 de Setembro de 2012. O Primeiro Encontro Nacional de História da Ciência teve lugar em 21 e 22 Julho de 2009, no seguimento d...


Botanical characterization of Guiera senegalensis leaves

Silva, Olga; Serrano, Rita; Gomes, Elsa Teixeira

Guiera senegalensis J. F. Gmel. (Combretaccae) is one of the most important West African medicinal plants, often used to treat a variety of microbial infections. The most frequently used plant part is the leaf, its medicinal use being corroborated by several in vitro antimicrobial activity studies. However, quality criteria for pharmaceutical use, including botanical identification, are not yet determined. Aimi...




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