5 documents found, page 1 of 1
PVA-Based Hydrogels Loaded with Diclofenac for Cartilage Replacement
Branco, Ana C.; Oliveira, Andreia S.; Monteiro, Inês; Nolasco, Pedro; Silva, Diana C.; Figueiredo-Pina, Célio; Colaço, Rogério; Serro, Ana P.Polyvinyl alcohol (PVA) hydrogels have been widely studied for cartilage replacement due to their biocompatibility, chemical stability, and ability to be modified such that they approximate natural tissue behavior. Additionally, they may also be used with advantages as local drug delivery systems. However, their properties are not yet the most adequate for such applications. This work aimed to develop new PVA-b...
PVA-based hydrogels loaded with diclofenac for cartilage replacement
Branco, Ana C.; Oliveira, Andreia S.; Monteiro, Inês; Nolasco, Pedro; Silva, Diana C.; Figueiredo-Pina, Célio G.; Colaço, Rogério; Serro, Ana P.Polyvinyl alcohol (PVA) hydrogels have been widely studied for cartilage replacement due to their biocompatibility, chemical stability, and ability to be modified such that they approximate natural tissue behavior. Additionally, they may also be used with advantages as local drug delivery systems. However, their properties are not yet the most adequate for such applications. This work aimed to develop new PVA-b...
Chemically crosslinked PVA hydrogels for cartilage substitution
Patacho, Inês; Oliveira, Andreia S.; Nolasco, Pedro; Colaço, Rogério; Serro, Ana P.
Development of polycarbonate urethane-based materials with controlled diclofena...
Oliveira, Andreia S.; Ferreira, Inês; Branco, Ana C.; Silva, João C.; Costa, Carolina; Nolasco, Pedro; Marques, Ana C.; Silva, Diana; Colaço, Rogérioydrogels are very promising human cartilage replacement materials since they are able to mimic its structure and properties. Besides, they can be used as platforms for drug delivery to reduce inflammatory postsurgical reactions. Polycarbonate urethane (PCU) has been used in orthopedic applications due to its long-term biocompatibility and bio-durability. In this work, PCU-based hydrogels with the ability to rel...
Diisodecylphthalate (DIDP) — a potential standard of moderate viscosity: surfac...
Oliveira, Carla Padrel de; Caetano, Fernando J. P.; Fareleira, João M. N. A.; Fernandes, Anabela C.; Serro, Ana P.; Almeida, Inês M. Simões deOur laboratory, along with several others, has been engaged in a project to determine the suitability of diisodecylphthalate (DIDP) as a standard reference material of viscosity for industrial purposes. As a part of that project, we have undertaken a study of the effects of surface tension and of impurities, of that liquid on viscosity measurements with routine, suspended level capillary instruments. For the fo...