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Effect of varying functional monomers in experimental self-adhesive composites:...

Ferreira, Marta Nunes; Neves Dos Santos, Marta; Fernandes, Inês; Marto, Carlos Miguel; Laranjo, Mafalda; Silva, Diana; Serro, Ana Paula

The aim was to evaluate the effects of adding different functional monomers to experimental self-adhesive composites (SACs) on polymerization kinetics, cell metabolic activity, and sealing ability. SACs were formulated using urethane dimethacrylate as the base monomer and triethylene glycol dimethacrylate. Additionally, 10 wt.% of distinct functional monomers were added - 10-methacryloyloxydecyl dihydrogen phos...


Recent Advances on 3D-Printed Zirconia-Based Dental Materials: A Review

Branco, Ana Catarina; Colaço, Rogério; Figueiredo-Pina, Célio; Serro, Ana Paula

Zirconia-based materials are widely used in dentistry due to their biocompatibility and suitable mechanical and tribological behavior. Although commonly processed by subtractive man- ufacturing (SM), alternative techniques are being explored to reduce material waste, energy con- sumption and production time. 3D printing has received increasing interest for this purpose. This systematic review intends to gather ...


A physiology-based mathematical model to understand drug delivery from contact ...

Toffoletto, Nadia; Saramago, Benilde; Serro, Ana Paula; Chauhan, Anuj

Objective: Therapeutic contact lenses, able to store drug and deliver it to the eye surface in a sustained fashion, gained interest as an effective and patient-friendly alternative to eye drops. Recent animal studies also demonstrated the presence of therapeutic drug levels in the back of the eye after wearing drug-loaded contact lenses, thus opening the possibility of treating the posterior segment without nee...


3D printing for dental applications

Figueiredo-Pina, Célio Gabriel; Serro, Ana Paula


Antiseptic-loaded casein hydrogels for wound dressings

Garcia, Leonor Vasconcelos; Silva, Diana; Costa, Maria Madalena; Armés, Henrique; Salema-Oom, Madalena; Saramago, Benilde; Serro, Ana Paula

Chronic wound treatment accounts for a substantial percentage of the medical expenses worldwide. Improving and developing novel wound care systems can potentially help to handle this problem. Wound dressings loaded with antiseptics may be an important tool for wound care, as they inhibit bacterial growth at the wound site. The goal of the present work was to investigate the potential of using casein hydrogel dr...


Book of Abstracts of 11th Iberian Conference on Tribology

Serro, Ana Paula; Branco, Ana Catarina Branco; Carneiro, Carla; Silva, Diana; Guedes, M.; Figueiredo-Pina, Célio


Effects of Non-Conventional Sterilisation Methods on PBO-Reinforced PVA Hydroge...

Pires, Tomás; Oliveira, Andreia Sofia; Marques, Ana Clara; Salema-Oom, Madalena; Figueiredo-Pina, Célio; Silva, Diana; Serro, Ana Paula

Articular cartilage (AC) degradation is a recurrent pathology that affects millions of people worldwide. Polyvinyl alcohol (PVA) hydrogels have been widely explored for AC replacement. How- ever, their mechanical performance is generally inadequate, and these materials need to be reinforced. Moreover, to be used in a clinical setting, such materials must undergo effective sterilisation. In this work, a PVA hydr...


3D bioprinting of novel κ-carrageenan bioinks : an algae-derived polysaccharide

Marques, Diana M. C.; Silva, João C.; Serro, Ana Paula; Cabral, Joaquim M. S.; Sanjuan-Alberte, Paola; Ferreira, Frederico C.

Novel green materials not sourced from animals and with low environmental impact are becoming increasingly appealing for biomedical and cellular agriculture applications. Marine biomaterials are a rich source of structurally diverse compounds with various biological activities. Kappa-carrageenan (κ-c) is a potential candidate for tissue engineering applications due to its gelation properties, mechanical strengt...


Effects of non-conventional sterilisation methods on PBO-reinforced PVA hydroge...

Pires, Tomás; Oliveira, Andreia Sofia; Marques, Ana Clara; Salema-Oom, Madalena; Figueiredo-Pina, Célio G.; Silva, Diana; Serro, Ana Paula

Articular cartilage (AC) degradation is a recurrent pathology that affects millions of people worldwide. Polyvinyl alcohol (PVA) hydrogels have been widely explored for AC replacement. However, their mechanical performance is generally inadequate, and these materials need to be reinforced. Moreover, to be used in a clinical setting, such materials must undergo effective sterilisation. In this work, a PVA hydrog...


In vivo study on the performance of therapeutic intraocular lens loaded with an...

Topete, Ana; Tang, Junmei; Lin, Quankui; Saramago, Benilde; Serro, Ana Paula


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