4 documents found, page 1 of 1
Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: E...
Taheri, Y; Sharifi-Rad, J; Antika, G; Yilmaz, YB; Tumer, TB; Abuhamdah, S; Chandra, S; Saklani, S; Kiliç, CS; Sestito, S; Dastan, SD; Kumar, MLuteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As many other natural flavonoids, it is often found in combination with glycosides in many fruits, vegetables, and plants, contributing to their biological and pharmacological value. Many preclinical studies report that luteolin present excellent antioxidant, anticancer, antimicrobial, neuroprotective, cardioprotective, a...
Chitosan nanoparticles as a promising tool in nanomedicine with particular emph...
Sharifi-Rad, J; Quispe, C; Butnariu, M; Rotariu, LS; Sytar, O; Sestito, S; Rapposelli, S; Akram, M; Iqbal, M; Krishna, A; Kumar, NVA; Braga, SSThe study describes the current state of knowledge on nanotechnology and its utilization in medicine. The focus in this manuscript was on the properties, usage safety, and potentially valuable applications of chitosan-based nanomaterials. Chitosan nanoparticles have high importance in nanomedicine, biomedical engineering, discovery and development of new drugs. The manuscript reviewed the new studies regarding ...
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safet...
Sharifi-Rad, J; Rayess, YE; Rizk, AA; Sadaka, C; Zgheib, R; Zam, W; Sestito, S; Rapposelli, S; Neffe-Skocinska, K; Zielinska, D; Salehi, B; Setzer, WNCurcumin, a yellow polyphenolic pigment from the Curcuma longa L. (turmeric) rhizome, has been used for centuries for culinary and food coloring purposes, and as an ingredient for various medicinal preparations, widely used in Ayurveda and Chinese medicine. In recent decades, their biological activities have been extensively studied. Thus, this review aims to offer an in-depth discussion of curcumin application...
Epibatidine: A promising natural alkaloid in health
Salehi, B; Sestito, S; Rapposelli, S; Peron, G; Calina, D; Sharifi-Rad, M; Sharopov, F; Martins, N; Sharifi-Rad, JEpibatidine is a natural alkaloid that acts at nicotinic acetylcholine receptors (nAChRs). The present review aims to carefully discuss the affinity of epibatidine and its synthetic derivatives, analogues to nAChRs for a4ß2 subtype, pharmacokinetic parameters, and its role in health. Published literature shows a low affinity and lack of binding of epibatidine and its synthetic analogues to plasma proteins, indi...