7 documents found, page 1 of 1
Myricetin bioactive effects: Moving from preclinical evidence to potential clin...
Taheri, Y; Suleria, HAR; Martins, N; Sytar, O; Beyatli, A; Yeskaliyeva, B; Seitimova, G; Salehi, B; Semwal, P; Painuli, S; Kumar, A; Azzini, ESeveral flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricet...
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safet...
Sharifi-Rad, J; Rayess, YE; Rizk, AA; Sadaka, C; Zgheib, R; Zam, W; Sestito, S; Rapposelli, S; Neffe-Skocinska, K; Zielinska, D; Salehi, B; Setzer, WNCurcumin, a yellow polyphenolic pigment from the Curcuma longa L. (turmeric) rhizome, has been used for centuries for culinary and food coloring purposes, and as an ingredient for various medicinal preparations, widely used in Ayurveda and Chinese medicine. In recent decades, their biological activities have been extensively studied. Thus, this review aims to offer an in-depth discussion of curcumin application...
Plant-derived bioactives and oxidative stress-related disorders: A key trend to...
Salehi, B; Azzini, E; Zucca, P; Varoni, EM; Kumar, NVA; Dini, L; Panzarini, E; Rajkovic, J; Fokou, PVT; Peluso, I; Mishra, AP; Nigam, M; Rayess, YEPlants and their corresponding botanical preparations have been used for centuries due to their remarkable potential in both the treatment and prevention of oxidative stress-related disorders. Aging and aging-related diseases, like cardiovascular disease, cancer, diabetes, and neurodegenerative disorders, which have increased exponentially, are intrinsically related with redox imbalance and oxidative stress. Hu...
Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysi...
Sharifi-Rad, M; Anil Kumar, NV; Zucca, P; Varoni, EM; Dini, L; Panzarini, E; Rajkovic, J; Tsouh Fokou, PV; Azzini, E; Peluso, I; Prakash Mishra, AOxidative stress plays an essential role in the pathogenesis of chronic diseases such as cardiovascular diseases, diabetes, neurodegenerative diseases, and cancer. Long term exposure to increased levels of pro-oxidant factors can cause structural defects at a mitochondrial DNA level, as well as functional alteration of several enzymes and cellular structures leading to aberrations in gene expression. The modern...
Phytochemicals in prostate cancer: From bioactive molecules to upcoming therape...
Salehi, B; Fokou, PVT; Yamthe, LRT; Tali, BT; Adetunji, CO; Rahavian, A; Mudau, FN; Martorell, M; Setzer, WN; Rodrigues, CF; Martins, N; Cho, WCProstate cancer is a heterogeneous disease, the second deadliest malignancy in men and the most commonly diagnosed cancer among men. Traditional plants have been applied to handle various diseases and to develop new drugs. Medicinal plants are potential sources of natural bioactive compounds that include alkaloids, phenolic compounds, terpenes, and steroids. Many of these naturally-occurring bioactive constitue...
The therapeutic potential of Apigenin
Salehi, B; Venditti, A; Sharifi-Rad, M; Kregiel, D; Sharifi-Rad, J; Durazzo, A; Lucarini, M; Santini, A; Souto, EB; Novellino, E; Antolak, H; Azzini, ESeveral plant bioactive compounds have exhibited functional activities that suggest they could play a remarkable role in preventing a wide range of chronic diseases. The largest group of naturally-occurring polyphenols are the flavonoids, including apigenin. The present work is an updated overview of apigenin, focusing on its health-promoting effects/therapeutic functions and, in particular, results of in vivo ...
Plant-derived bioactives in oral mucosal lesions: A key emphasis to Curcumin, L...
Salehi, B; Jornet, PL; López, EPF; Calina, D; Sharifi-Rad, M; Ramírez-Alarcón, K; Forman, K; Fernández, M; Martorell, M; Setzer, WN; Martins, NOral mucosal lesions have many etiologies, including viral or bacterial infections, local trauma or irritation, systemic disorders, and even excessive alcohol and tobacco consumption. Folk knowledge on medicinal plants and phytochemicals in the treatment of oral mucosal lesions has gained special attention among the scientific community. Thus, this review aims to provide a brief overview on the traditional know...