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Natural Coumarins: Exploring the Pharmacological Complexity and Underlying Mole...

Sharifi-Rad, J; Martins, N; López-Jornet, P; Lopez, EPF; Harun, N; Yeskaliyeva, B; Beyatli, A; Sytar, O; Shaheen, S; Sharopov, F; Taheri, Y; Docea, AO

Coumarins belong to the benzopyrone family commonly found in many medicinal plants. Natural coumarins demonstrated a wide spectrum of pharmacological activities, including anti-inflammatory, anticoagulant, anticancer, antibacterial, antimalarial, casein kinase-2 (CK2) inhibitory, antifungal, antiviral, Alzheimer's disease inhibition, neuroprotective, anticonvulsant, phytoalexins, ulcerogenic, and antihypertensi...


Glycyrrhiza Genus: Enlightening Phytochemical Components for Pharmacological an...

Sharifi-Rad, J; Quispe, C; Herrera-Bravo, J; Belén, LH; Kaur, R; Kregiel, D; Uprety, Y; Beyatli, A; Yeskaliyeva, B; Kirkin, C; Özçelik, B; Sen, S

The Glycyrrhiza genus, generally well-known as licorice, is broadly used for food and medicinal purposes around the globe. The genus encompasses a rich pool of bioactive molecules including triterpene saponins (e.g., glycyrrhizin) and flavonoids (e.g., liquiritigenin, liquiritin). This genus is being increasingly exploited for its biological effects such as antioxidant, antibacterial, antifungal, anti-inflammat...


Cucurbita plants: From farm to industry

Salehi, B; Sharifi-Rad, J; Capanoglu, E; Adrar, N; Catalkaya, G; Shaheen, S; Jaffer, M; Giri, L; Suyal, R; Jugran, AK; Calina, D; Docea, AO

The Cucurbita genus, a member of Cucurbitaceae family, also known as cucurbits, is native to the Americas. Genus members, like Cucurbita pepo and Cucurbita maxima, have been used for centuries in folk medicine for treating gastrointestinal diseases and intestinal parasites. These pharmacological effects are mainly attributed to their phytochemical composition. Indeed, Cucurbita species are a natural source of c...


Apium plants: Beyond simple food and phytopharmacological applications

Salehi, B; Venditti, A; Frezza, C; Yücetepe, A; Altuntas, Ü; Uluata, S; Butnariu, M; Sarac, I; Shaheen, S; Petropoulos, SA; Matthews, KR; Kiliç, CS

Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycos...


Cucurbits plants: A key emphasis to its pharmacological potential

Salehi, B; Capanoglu, E; Adrar, N; Catalkaya, G; Shaheen, S; Jaffer, M; Giri, L; Suyal, R; Jugran, A; Calina, D; Docea, A; Kamiloglu, S; Kregiel, D

Cucurbita genus has received a renowned interest in the last years. This plant species, native to the Americas, has served worldwide folk medicine for treating gastrointestinal diseases and intestinal parasites, among other clinical conditions. These pharmacological effects have been increasingly correlated with their nutritional and phytochemical composition. Among those chemical constituents, carotenoids, toc...


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