3 documents found, page 1 of 1
Application of Hazard Functions to Investigate Recurrence After Curative-Intent...
Lima, H; Alaimo, L; Brown, Z; Endo, Y; Moazzam, Z; Tsilimigras, D; Shaikh, C; Resende, V; Guglielmi, A; Ratti, F; Aldrighetti, L; Pinto Marques, HBackground: Defining patterns and risk of recurrence can help inform surveillance strategies and patient counselling. We sought to characterize peak hazard rates (pHR) and peak time of recurrence among patients who underwent resection of hepatocellular carcinoma (HCC). Methods: 1434 patients who underwent curative-intent resection of HCC were identified from a multi-institutional database. Hazard, patterns, and...
TAC Score Better Predicts Survival Than the BCLC Following Resection of Hepatoc...
Lima, H; Endo, Y; Moazzam, Z; Alaimo, L; Shaikh, C; Munir, M; Resende, V; Guglielmi, A; Pinto Marques, H; Cauchy, F; Lam, V; Poultsides, G; Popescu, IBackground: Heterogeneity in hepatocellular carcinoma (HCC) still exists within the Barcelona clinic liver cancer (BCLC) subcategories. We developed a simple model to better discriminate and predict prognosis following resection. Methods: Patients who underwent curative-intent resection for HCC were identified from a multi-institutional database. Predictive factors of survival were identified to develop TAC (tu...
Tumor Burden Score and Serum Alpha-fetoprotein Subclassify Intermediate-Stage H...
Lima, H; Endo, Y; Alaimo, L; Moazzam, Z; Munir, M; Shaikh, C; Resende, V; Guglielmi, A; Pinto Marques, H; Cauchy, F; Lam, V; Poultsides, G; Popescu, IBackground: Resection of Barcelona Clinic Liver Cancer (BCLC) intermediate-stage hepatocellular carcinoma (HCC) remains controversial. While not recommended by the BCLC algorithm, some patients may indeed benefit from hepatectomy. We sought to identify that subset of patients who might derive long-term survival benefit from resection. Methods: Intermediate-stage HCC patients who underwent curative-intent resect...