12 documents found, page 1 of 2

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Exploring the therapeutic potential of cannabinoids in cancer by modulating sig...

Faiz, Manal Bint; Naeem, Faiza; Irfan, Muhammad; Aslam, Muhammad Adeel; Estevinho, Leticia M.; Ateşşahin, Dilek Arslan; Alshahrani, Asma M.

For centuries, cannabinoids have been utilized for their medicinal properties, particularly in Asian and South-Asian countries. Cannabis plants, known for their psychoactive and non-psychoactive potential, were historically used for spiritual and remedial healing. However, as cannabis became predominantly a recreational drug, it faced prohibition. Recently, the therapeutic potential of cannabinoids has sparked ...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Revolutionizing fruit juice: exploring encapsulation techniques for bioactive c...

Gómez-Gaete, Carolina; Avendaño-Godoy, Javier; Escobar-Avello, Danilo; Campos-Requena, Víctor H.; Rogel-Castillo, Cristian; Estevinho, Leticia M.

Bioactive compounds in food and beverages, including fruit juices, are susceptible to degradation or oxidation during processing and storage. This vulnerability can lead to a reduction in nutritional value and overall quality of the products. The objective of this research is to explore the potential of encapsulation techniques in preserving and enhancing the nutritional value of fruit juices. The encapsulation...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Future trends in food science and foodomics: a perspective view by the editoria...

Ibáñez, Elena; Bicchi, Carlo; Capozzi, Francesco; Chen, Yi; Coppola, Francesca; Fanali, Salvatore; Ferreira, Sandra R. S.; Fischer, Markus

In this perspective article, several internationally recognized experts, members of the editorial team of this journal, discuss a selection of current hot topics identified in Food Science and Foodomics. The topics are comprised of the main areas of Food Science and Foodomics, namely, food safety, food authenticity, food processing, and food bioactivity. Logically, several of the discussed topics involve more t...


Chemotherapeutic properties and side-effects associated with the clinical pract...

Sousa-Pimenta, Mário; Estevinho, Leticia M.; Szopa, Agnieszka; Basit, Mahnoor; Khan, Khushbukhat; Armaghan, Muhammad; Ibrayeva, Manshuk

Over the years, many biological and synthetic agents have been explored and tested in attempts to halt the spread of cancer and/or cure it. Currently, several natural compounds have and are being considered in this regard. For example, paclitaxel is a potent anticancer drug that originates from the tree Taxus brevifolia. Paclitaxel has several derivatives, namely, docetaxel and cabazitaxel. These agents work by...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Resveratrol biotechnological applications: enlightening its antimicrobial and a...

Sharifi-Rad, Javad; Quispe, Cristina; Durazzo, Alessandra; Lucarini, Massimo; Souto, Eliana B.; Santini, Antonello; Imran, Muhammad; Moussa, Ashaimaa Y.

Introduction Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a polyphenol obtained from diverse groups of plants, especially in the muscadine grape, red wine, lingonberry, cranberry and redcurrant. Resveratrol's health benefits were first highlighted in the study of the French paradox, which opened up an expansive research endeavor into this compound. Ever since, an array of pharmacological activities, includ...


Phenolic bioactives as antiplatelet aggregation factors: the pivotal ingredient...

Sharifi-Rad, Javad; Quispe, Cristina; Zam, Wissam; Kumar, Manoj; Cardoso, Susana M.; Pereira, Olívia R.; Ademiluyi, Adedayo O.; Adeleke, Oluwakemi

Cardiovascular diseases (CVD) are one of the main causes of mortality in the world. The development of these diseases has a specific factor—alteration in blood platelet activation. It has been shown that phenolic compounds have antiplatelet aggregation abilities and a positive impact in the management of CVD, exerting prominent antioxidant, anti-inflammatory, antitumor, cardioprotective, antihyperglycemic, and ...

Date: 2021   |   Origin: Biblioteca Digital do IPB

Ginger (Zingiber officinale Roscoe) as a nutraceutical: Focus on the metabolic,...

Pagano, Ester; Souto, Eliana B.; Durazzo, Alessandra; Sharifi-Rad, Javad; Lucarini, Massimo; Souto, Selma E.; Salehi, Bahare; Zam, Wissam

Ginger (from the rizhome of Zingiber officinale Roscoe) has been widely used in ethnomedicine for the cure of several ailments. Main active ingredients include phenolic compounds named gingerols. In modern phytotherapy, ginger preparations are predominantly used to counteract nausea and vomiting in pregnant women. However, a number of other pharmacological actions of potential therapeutic interest, which might ...


The therapeutic potential of wogonin observed in preclinical studies

Sharifi-Rad, Javad; Herrera-Bravo, Jesús; Salazar, Luis A.; Shaheen, Shabnum; Abdulmajid Ayatollahi, Seyed; Kobarfard, Farzad; Imran, Muhammad

Wogonin is a flavonoid found in different plants such as roots of Scutellaria baicalensis Georgi distributed mainly in Asia and Europe. Dried root extracts of S. baicalensis with high content of wogonin, popularly known as "Huang-Qin" or Chinese or baical skullcap, have been used for long time in traditional Chinese medicine. Several health benefits are attributed to wogonin and derivatives showing anti-inflamm...


Areca catechu - from farm to food and biomedical applications

Salehi, Bahare; Konovalov, Dmitry A.; Fru, Pascaline; Kapewangolo, Petrina; Peron, Gregorio; Ksenija, Mileski S.; Cardoso, Susana M.; Pereira, Olívia R.

The family Arecaceae includes 181 genera and 2,600 species with a high diversity in physical characteristics. Areca plants, commonly palms, which are able to grow in nearly every type of habitat, prefer tropical and subtropical climates. The most studied species Areca catechu L. contains phytochemicals as phenolics and alkaloids with biological properties. The phenolics are mainly distributed in roots followed ...

Date: 2020   |   Origin: Biblioteca Digital do IPB

Kaempferol: a key emphasis to its anticancer potential

Imran, Muhammad; Salehi, Bahare; Sharifi-Rad, Javad; Gondal, Tanweer; Saeed, Farhan; Imran, Ali; Shahbaz, Muhammad; Fokou, Patrick; Khan, Haroon

A marked decrease in human cancers, including breast cancer, bone cancer, and cervical cancer, has been linked to the consumption of vegetable and fruit, and the corresponding chemoprotective e ect has been associated with the presence of several active molecules, such as kaempferol. Kaempferol is a major flavonoid aglycone found in many natural products, such as beans, bee pollen, broccoli, cabbage, capers, ca...

Date: 2019   |   Origin: Biblioteca Digital do IPB

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