14 documents found, page 1 of 2
Global age-sex-specific mortality, life expectancy, and population estimates in...
Schumacher, AE; Kyu, HH; Aali, A; Abbafati, C; Abbas, J; Abbasgholizadeh, R; Abbasi, MA; Abbasian, M; Abd ElHafeez, S; Abdelmasseh, M; Abd Elsalam, SBackground: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides n...
The overlapping burden of the three leading causes of disability and death in s...
Reiner, RC; Welgan, CA; Troeger, CE; Baumann, MM; Weiss, DJ; Deshpande, A; Blacker, BF; Miller Petrie, MK; Earl, L; Bhatt, S; Abolhassani, HDespite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa (SSA). The spatial burden of each of these diseases has been estimated subnationally across SSA, yet no prior analyses have examined the pattern of their com...
Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials
Das, G; Shin, HS; Leyva-Gómez, G; Prado-Audelo, MLD; Cortes, H; Singh, YD; Panda, MK; Mishra, AP; Nigam, M; Saklani, S; Chaturi, PK; Martorell, MIn recent decades, interest in the Cordyceps genus has amplified due to its immunostimulatory potential. Cordyceps species, its extracts, and bioactive constituents have been related with cytokine production such as interleukin (IL)-1ß, IL-2, IL-6, IL-8, IL-10, IL-12, and tumor necrosis factor (TNF)-a, phagocytosis stimulation of immune cells, nitric oxide production by increasing inducible nitric oxide synthas...
Conifers phytochemicals: A valuable forest with therapeutic potential
Bhardwaj, K; Silva, AS; Atanassova, M; Sharma, R; Nepovimova, E; Musilek, K; Sharma, R; Alghuthaymi, MA; Dhanjal, DS; Nicoletti, M; Sharma, BConifers have long been recognized for their therapeutic potential in different disorders. Alkaloids, terpenes and polyphenols are the most abundant naturally occurring phytochemicals in these plants. Here, we provide an overview of the phytochemistry and related commercial products obtained from conifers. The pharmacological actions of different phytochemicals present in conifers against bacterial and fungal i...
Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literatu...
Islam, MT; Quispe, C; Herrera-Bravo, J; Sarkar, C; Sharma, R; Garg, N; Fredes, LI; Martorell, M; Alshehri, MM; Sharifi-Rad, J; Dastan, SD; Calina, DDengue remains one of the most serious and widespread mosquito-borne viral infections in human beings, with serious health problems or even death. About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths. Dengue virus infection is especially transmitted through bites of Aedes mosquitos, hugely spread in tropical and subtropical envi...
Potential usage of edible mushrooms and their residues to retrieve valuable sup...
Kumar, H; Bhardwaj, K; Sharma, R; Nepovimova, E; Martins, N; Dhanjal, DS; Singh, R; Chopra, C; Verma, R; Abd-Elsalam, KA; Tapwal, A; Musilek, KCurrently, the food and agricultural sectors are concerned about environmental problems caused by raw material waste, and they are looking for strategies to reduce the growing amount of waste disposal. Now, approaches are being explored that could increment and provide value-added products from agricultural waste to contribute to the circular economy and environmental protection. Edible mushrooms have been glob...
Naturally Occurring Bioactives as Antivirals: Emphasis on Coronavirus Infection
Ayatollahi, SA; Sharifi-Rad, J; Tsouh Fokou, PV; Mahady, GB; Ansar Rasul Suleria, H; Krishna Kapuganti, S; Gadhave, K; Giri, R; Garg, N; Sharma, RThe current coronavirus disease (COVID-19) outbreak is a significant threat to human health and the worldwide economy. Coronaviruses cause a variety of diseases, such as pneumonia-like upper respiratory tract illnesses, gastroenteritis, encephalitis, multiple organ failure involving lungs and kidneys which might cause death. Since the pandemic started there have been more than 107 million COVID-19 infections ca...
Role of vacha (Acorus calamus Linn.) in neurological and metabolic disorders: E...
Sharma, V; Sharma, R; Gautam, DNS; Kuca, K; Nepovimova, E; Martins, NVacha (Acorus calamus Linn. (Acoraceae)) is a traditional Indian medicinal herb, which is practiced to treat a wide range of health ailments, including neurological, gastrointestinal, respiratory, metabolic, kidney, and liver disorders. The purpose of this paper is to provide a comprehensive up-to-date report on its ethnomedicinal use, phytochemistry, and pharmacotherapeutic potential, while identifying potenti...
Influence of family environment and tobacco addiction: A short report from a po...
Sharma, R; Martins, N; Tripathi, A; Caponnetto, P; Garg, N; Nepovimova, E; Kuca, K; Kumar Prajapati, PBackground: The initiation of tobacco addiction is complex, and several factors contribute to the onset of this behavior. It is presumed that the influence of family environment may pose a key factor in tobacco addiction. Tobacco-use has been highly observed in the Jamnagar district of Saurashtra region of Gujarat, India. No earlier study has focused on determining the pervasiveness of tobacco-use in families o...
Neuroprotective potential of Myrica esulenta in Haloperidol induced Parkinson's...
Kabra, A; Baghel, US; Hano, C; Martins, N; Khalid, M; Sharma, RBackground: Myrica esculenta is a notable therapeutic plant widely utilized in Indian system of medicine. Ayurvedic literature reported fruit and bark of this plant is used in gulma, jvara, arsa, grahani, pandu roga, hrillasa, mukha roga, kasa, svasa, agnimandhya, aruchi, meha, and kantharoga. Objective: The present study aimed to investigate the neuroprotective potential of “Himalayan Bayberry” (Myrica esculen...