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Enzyme immunoassays (EIA) for serodiagnosis of human leptospirosis
Fortes-Gabriel, Elsa; Guedes, Mariana Soares; Shetty, Advait; Gomes, Charles Klazer; Carreira, Teresa; Vieira, Maria Luísa; Esteves, LisaThe laborious microscopic agglutination test (MAT) is the gold standard serologic test for laboratory diagnosis of leptospirosis. We developed EIA based serologic assays using recombinant proteins (rLigA, rLigB, rLipL32) and whole-cell extracts from eight Leptospira serovars as antigen and assessed the diagnostic performance of the new assay within each class, against MAT positive (MAT+) human sera panels from ...
Date: 2022
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Origin: Repositório Institucional da UNL