5 documents found, page 1 of 1
Numerical evaluation and experimental validation of fluid flow behavior within ...
Carvalho, Violeta Meneses; Gonçalves, Inês M.; Rodrigues, Nelson; Sousa, Paulo; Pinto, Vânia; Minas, Graça; Kaji, Hirokazu; Shin, Su RyonBy combining biomaterials, cell culture, and microfluidic technology, organ-on-a-chip (OoC) platforms have the ability to reproduce the physiological microenvironment of human organs. For this reason, these advanced microfluidic devices have been used to resemble various diseases and investigate novel treatments. In addition to the experimental assessment, numerical studies of biodevices have been performed aim...
Advancing blood-brain barrier-on-a-chip models through numerical simulations
Carvalho, Violeta Meneses; Rodrigues, Raquel O.; Shin, Su Ryon; Lima, Rui; Teixeira, S. F. C. F.Researchers have placed engineered or natural tissues within microfuidic chips originating the so-called organ-on-a-chip (OoC) devices. With this technology, organ models can be subjected to phenomena that replicate the complex in vivo biological environment. Furthermore, the OoC devices constitute a more valuable, cost-efective and ethical option when compared to assays performed in animal models for disease r...
Correction: Diniz et al. Silver Nanoparticles-Composing Alginate/Gelatine Hydro...
Diniz, Flavia Resende; Maia, Romerito Cesar A. P.; de Andrade, Lucas Rannier M.; Andrade, Luciana Nalone; Vinicius Chaud, MarcoIn the original publication, there was a mistake in Figure 6 as published [...]
Suturable elastomeric tubular grafts with patterned porosity for rapid vascular...
Bellani, Caroline Faria; Yue, Kan; Flaig, Florence; Hébraud, Anne; Ray, Pengfei; Annabi, Nasim; Selistre De Araújo, Heloísa SobreiroMade available in DSpace on 2021-06-25T10:59:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-01; Vascularization is considered to be one of the key challenges in engineering functional 3D tissues. Engineering suturable vascular grafts containing pores with diameter of several tens of microns in tissue engineered constructs may provide an instantaneous blood perfusion through the grafts improving ce...
Silver nanoparticles-composing alginate/gelatine hydrogel improves wound healin...
Diniz, Flavia Resende; Maia, Romerito Cesar A. P.; Andrade, Lucas Rannier; Andrade, Luciana Nalone; Vinicius Chaud, Marco; Silva, Classius Ferreira daPolymer hydrogels have been suggested as dressing materials for the treatment of cutaneous wounds and tissue revitalization. In this work, we report the development of a hydrogel composed of natural polymers (sodium alginate and gelatin) and silver nanoparticles (AgNPs) with recognized antimicrobial activity for healing cutaneous lesions. For the development of the hydrogel, different ratios of sodium alginate ...