2 documents found, page 1 of 1
The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA M...
Leal, Graciano; Comprido, Diogo; Luca, Pasqualino De; Morais, Eduardo Manuel Firmo; Rodrigues, Luís; Mele, Miranda; Santos, Ana R.; Costa, Rui O.Brain-derived neurotrophic factor (BDNF) is an important mediator of long-term synaptic potentiation (LTP) in the hippocampus. The local effects of BDNF depend on the activation of translation activity, which requires the delivery of transcripts to the synapse. In this work, we found that neuronal activity regulates the dendritic localization of the RNA-binding protein heterogeneous nuclear ribonucleoprotein K ...
The RNA-binding protein hnRNP K mediates the effect of BDNF on dendritic mRNA m...
Leal, Graciano; Comprido, Diogo; Luca, Pasqualino de; Morais, Eduardo; Rodrigues, Luís; Mele, Miranda; Santos, Ana R.; Costa, Rui O.; Pinto, Maria JoanaBrain-derived neurotrophic factor (BDNF) is an important mediator of long-term synaptic potentiation (LTP) in the hippocampus. The local effects of BDNF depend on the activation of translation activity, which requires the delivery of transcripts to the synapse. In this work, we found that neuronal activity regulates the dendritic localization of the RNA-binding protein heterogeneous nuclear ribonucleoprotein K ...