5 documents found, page 1 of 1
Paclitaxel: Application in Modern Oncology and Nanomedicine-Based Cancer Therapy
Sharifi-Rad, J; Quispe, C; Patra, JK; Singh, YD; Panda, MK; Das, G; Adetunji, CO; Michael, OS; Sytar, O; Polito, L; Živkovic, J; Martins, NPaclitaxel is a broad-spectrum anticancer compound, which was derived mainly from a medicinal plant, in particular, from the bark of the yew tree Taxus brevifolia Nutt. It is a representative of a class of diterpene taxanes, which are nowadays used as the most common chemotherapeutic agent against many forms of cancer. It possesses scientifically proven anticancer activity against, e.g., ovarian, lung, and brea...
Phenolic Bioactives as Antiplatelet Aggregation Factors: The Pivotal Ingredient...
Sharifi-Rad, J; Quispe, C; Zam, W; Kumar, M; Cardoso, SM; Pereira, OR; Ademiluyi, AO; Adeleke, O; Moreira, AC; Živkovic, J; Noriega, F; Ayatollahi, SACardiovascular diseases (CVD) are one of the main causes of mortality in the world. The development of these diseases has a specific factor-alteration in blood platelet activation. It has been shown that phenolic compounds have antiplatelet aggregation abilities and a positive impact in the management of CVD, exerting prominent antioxidant, anti-inflammatory, antitumor, cardioprotective, antihyperglycemic, and ...
Chemical Composition, Biological Activity, and Health-Promoting Effects of With...
Sharifi-Rad, J; Quispe, C; Ayatollahi, SA; Kobarfard, F; Staniak, M; Stepien, A; Czopek, K; Sen, S; Acharya, K; Matthews, KR; Sener, B; Devkota, HPThe Withania genus comes from the Solanaceae family and includes around 23 species, spread over some areas of the Mediterranean, Asia, and East Africa. Widely used in traditional medicine for thousands of years, these plants are rich in secondary metabolites, with special emphasis on steroidal lactones, named withanolides which are used as ingredients in numerous formulations for a plethora of diseases, such as...
Liposomal cytarabine as cancer therapy: From chemistry to medicine
Salehi, B; Selamoglu, Z; Mileski, KS; Pezzani, R; Redaelli, M; Cho, WC; Kobarfard, F; Rajabi, S; Martorell, M; Kumar, P; Martins, N; Santra, TSCancer is the second leading cause of death worldwide. The main modality to fight against cancer is surgery, radiotherapy, and chemotherapy, and more recently targeted therapy, gene therapy and immunotherapy, which play important roles in treating cancer patients. In the last decades, chemotherapy has been well developed. Nonetheless, administration of the drug is not always successful, as limited drug dosage c...
Prosopis plant chemical composition and pharmacological attributes: Targeting c...
Sharifi-Rad, J; Kobarfard, F; Ata, A; Ayatollahi, SA; Khosravi-Dehaghi, N; Jugran, AK; Tomas, M; Capanoglu, E; Matthews, KR; Popovic-Djordjevic, JMembers of the Prosopis genus are native to America, Africa and Asia, and have long been used in traditional medicine. The Prosopis species most commonly used for medicinal purposes are P. africana, P. alba, P. cineraria, P. farcta, P. glandulosa, P. juliflora, P. nigra, P. ruscifolia and P. spicigera, which are highly effective in asthma, birth/postpartum pains, callouses, conjunctivitis, diabetes, diarrhea, e...