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ARIA Digital Anamorphosis: Digital Transformation of Health and Care in Airway ...

Bousquet, J; Anto, JM; Bachert, C; Haahtela, T; Zuberbier, T; Czarlewski, W; Bedbrook, A; Bosnic-Anticevich, S; Walter Canonica, G; Cardona, V; Costa, E

Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validate...


Anaphylaxis in an emergency department: a retrospective 10-year study in a tert...

Alen Coutinho, I.; Ferreira, D; Regateiro, FS; Pita, J; Ferreira, M; Martins, JF; Fonseca, IA; Loureiro, C; Todo-Bom, A

Background. Anaphylaxis is a potentially fatal medical emergency. The frequency of hospital admissions for anaphylaxis seems to be increasing in the recent decades. Objective. Characterize the patients admitted for anaphylaxis to the adult emergency department (ED) of a tertiary care hospital over a 10-year period, discriminating aetiologies, clinical features and therapy administered. Methods. Retrospective, d...


Omalizumab for Severe Asthma: Beyond Allergic Asthma.

Loureiro, C; Anmaral, L; Ferreira, A; Lima, R; Pardal, C; Fernandes, I; Semedo, L; Arrobas, A

Different subsets of asthma patients may be recognized according to the exposure trigger and the frequency and severity of clinical signs and symptoms. Regarding the exposure trigger, generally asthma can be classified as allergic (or atopic) and nonallergic (or nonatopic). Allergic and nonallergic asthma are distinguished by the presence or absence of clinical allergic reaction and in vitro IgE response to spe...


The Portuguese Severe Asthma Registry: Development, Features, and Data Sharing ...

Sá-Sousa A1, A; Fonseca, JA; Pereira, AM; Ferreira, A; Arrobas, A; Mendes, A; Drummond, M; Videira, W; Costa, T; Farinha, P; Soares, J; Rocha, P

The Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation ...


The Portuguese Severe Asthma Registry: Development, Features, and Data Sharing ...

Sá-Sousa, A; Fonseca, J; Pereira, A; Ferreira, A; Arrobas, A; Mendes, A; Drummond, M; Videira, W; Costa, T; Farinha, P; Soares, J; Rocha, P; Todo-Bom, A

The Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation ...


Prevalence of Late-Onset Pompe Disease in Portuguese Patients with Diaphragmati...

Guimarães, MJ; Winck, JC; Conde, B; Mineiro, A; Raposo, M; Moita, J; Marinho, A; Silva, JM; Pires, N; André, S; Loureiro, C

Pompe disease is a rare autosomal recessive neuromuscular disorder caused by acid α-glucosidase enzyme (GAA) deficiency and divided into two distinct variants, infantile- and late-onset. The late-onset variant is characterized by a spectrum of phenotypic variation that may range from asymptomatic, to reduced muscle strength and/or diaphragmatic paralysis. Since muscle strength loss is characteristic of several ...


Asthma and rhinitis have different genetic profiles for IL13, IL17A and GSTP1 p...

Resende, EP; Todo-Bom, A; Loureiro, C; Mota-Pinto, A; Oliveiros, B; Mesquita, L; Silva, HC

BACKGROUND: Asthma and rhinitis have a complex etiology, depending on multiple genetic and environmental risk factors. An increasing number of susceptibility genes are currently being identified, but the majority of reported associations have not been consistently replicated across populations of different genetic backgrounds. PURPOSE: To evaluate whether polymorphisms of IL4R (rs1805015), IL13 (rs20541), IL17A...


Manual de boas práticas de gestão dos espaços florestais na bacia drenante da A...

Guiomar, Nuno; Palheiro, P; Loureiro, C; Carvalho, CR; Tomé, J; Fernandes, JP

No âmbito do Projecto “Nascentes para a Vida” foram concluídas tarefas que se encontram sintetizadas neste documento, em particular no que se refere às seguintes tarefas: • Tarefa 3.1: Medidas a implementar ao nível das linhas de água afluentes à Albufeira de Castelo do Bode; • Tarefa 3.2: Implementação de um programa de gestão de matos e promoção da biodiversidade na envolvente da Albufeira de Castelo do Bode;...


MÓDULO 7 - Desenvolvimento e Neurologia

Bento, C; Rodrigues, F; Oliveira, G; Lopes, MF; Brito, MJ; Diogo, L; Loureiro, C; Santos, I; Cordinhã, C; Canha, J; Mirante, A; Baptista, N; Jorge, A



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