Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:18:14Z No. of bitstreams: 0; Made available in DSpace on 2014-05-27T11:18:14Z (GMT). No. of bitstreams: 0 Previous issue date: 1997-05-16; Laboratory of Pharmacology Faculty of Pharmaceutical Sciences University of Sao Paulo, Ribeirão Preto, SP; Disc. of Pharmacology Faculty of Odontology University Estadual Paulista Júli...
The antinociceptive effects of interleukin (IL)-4, -10, and -13 were investigated in two different experimental pain models. Our results showed that pretreatment (30 min) with IL-4 (1–5 ng/animal), IL-10 (0.4–10 ng/animal), or IL-13 (0.4 –2.5 ng/animal) inhibited the writhing response induced by the i.p. administration of acetic acid (53–89%) or zymosan (63–74%) in mice, and the knee joint incapacitation induce...