2 documents found, page 1 of 1
Efficacy of a broad host range lytic bacteriophage against E. coli adhered to u...
Sillankorva, S; Oliveira, D; Moura, A; Henriques, M; Faustino, A; Nicolau, A; Azeredo, JPersistent urinary tract infections (UTI) are often caused by E. coli adhered to urothelium. This type of cells is generally recognized as very tolerant to antibiotics which renders difficult the treatment of chronic UTI. This study investigates the use of lytic bacteriophages as alternative antimicrobial agents, particularly the interaction of phages with E. coli adhered to urothelium and specifically determin...
Use of newly isolated phages for control of Pseudomonas aeruginosa PAO1 and ATC...
Pires, D; Sillankorva, S; Faustino, A; Azeredo, JPseudomonas aeruginosa is a relevant opportunistic pathogen involved in nosocomial infections that frequently shows low antibiotic susceptibility. One of its virulence factors is associated with the ability to adhere to surfaces and form virulent biofilms. This work describes the isolation and characterization of lytic phages capable of infecting antibiotic-resistant P. aeruginosa strains. In addition, characte...