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Bacteriophage control of infectious biofilms

Meneses, Luciana Amorim Perestrelo; Sillankorva, Sanna M.; Azeredo, Joana

Biofilm formation, a strategy of bacterial survival, is a significant concern in different areas, including health, where infectious biofilms are very difficult to combat with conventional antimicrobial therapies. Bacteriophages, the viruses that infect bacteria, are promising agents to prevent and control biofilm-related infections. This chapter describes a series of standard procedures that can be used to stu...


Levofloxacin-loaded microneedles produced using 3D-printed molds for Klebsiella...

Vinayakumar, K. B.; Silva, Maria Daniela; Martins, Artur; Mundy, Stephen; González-Losada, Pedro; Sillankorva, Sanna M.

Additive manufacturing advancements contribute considerably to several fields, and its use in the medical field is gaining attention due to its easily customizable option (patient-specific), low cost, and fast turnout time in developing drug delivery and diagnostic tools. Here, wereport the fabrication of a microneedle (MN) platform using a stereolithography 3D printer, varying the 3D printing angle and aspect ...


Characterization of PHBV films loaded with FO1 bacteriophage using polyvinyl al...

Costa, Maria J.; Pastrana, Lorenzo M.; Teixeira, J. A.; Sillankorva, Sanna M.; Cerqueira, Miguel A.

There is a current demand for novel active food packaging solutions using biodegradable materials and no chemical antimicrobial compounds, to ensure food quality and safety. This work involved the incorporation of Salmonella Enteritidis bacteriophage Felix O1, for potential use as an anti-Salmonella agent, into polyvinyl alcohol (PVOH) coatings and fibers deposited by casting and electrospinning on polyhydroxyb...


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