5 documents found, page 1 of 1
DNA Methyltransferase Expression (DNMT1, DNMT3a, and DNMT3b) as a Potential Bio...
Camacho, Pedro; Ribeiro, Edna; Pereira, Bruno; Nascimento, João; Caldeira Rosa, Paulo; Henriques, José; Barrão, Sandra; Sadio, Silvia; Quendera, BrunoPublisher Copyright: © 2025 by the authors.; Background/Objectives: Age-related macular degeneration (AMD) is a global cause of vision loss, with limited therapeutic options highlighting the need for effective biomarkers. This study aimed to characterize plasma DNA methyltransferase expression (DNMT1, DNMT3A, and DNMT3B) in AMD patients and explore divergent expression patterns across different stages of AMD. M...
Epidemiology and risk factors for Schistosoma spp. infection in adult populatio...
Serra, João Tiago; Silva, Carina; Sidat, Mohsin; Belo, Silvana; Ferreira, Pedro; Ferracini, Natália; Kaminstein, Daniel; Conceição, CSchistosomiasis is a neglected tropical disease that remains an important public health problem. Mozambique is one of the countries with the highest prevalence of the disease. Adults with chronic schistosomiasis can act as a reservoir for continued infection transmission. Data about schistosomiasis in this population in Mozambique is limited. In order to determine schistosomiases prevalence and risk factors in ...
DNA methyltransferase expression (DNMT1, DNMT3a and DNMT3b) as a potential biom...
Camacho, Pedro; Ribeiro, Edna; Pereira, Bruno; Varandas, Teresa; Nascimento, João; Henriques, José; Dutra-Medeiros, Marco; Delgadinho, MarianaFunding Information: This project was partially supported by an IDI&CA grant IPL/2021/DiffMeDiME_ESTeSL by H&TRC- Health & Technology Research Center, ESTeSL- Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa and by Retina Institute of Lisbon (IRL).; Purpose: DNA methylation is involved in Diabetic Retinopathy progression showing a metabolic memory mechanism. However, the association of DN...
Gut microbiota profile of COVID-19 patients
Nobre, José Guilherme; Delgadinho, Mariana; Silva, Carina; Mendes, Joana; Mateus, Vanessa; Ribeiro, Edna; Costa, Diogo Alpuim; Lopes, MiguelFunding Information: The authors acknowledge financial support from Instituto Politécnico de Lisboa that supported this project with the grant Microcovid. This project was also partially supported by FCT/MCTES (UIDB/05608/2020 and UIDP/05608/2020). Publisher Copyright: Copyright © 2022 Nobre, Delgadinho, Silva, Mendes, Mateus, Ribeiro, Costa, Lopes, Pedroso, Trigueiros, Rodrigues, de Sousa and Brito.; Backgroun...
Glucose Homeostasis in Obese Women Is Not Associated to Unacylated Ghrelin Plas...
Veiga, Luisa; Brito, Miguel; Silva, Carina; Silva-Nunes, JoséIntroduction: Unacylated ghrelin (UAG) is the major form of circulating ghrelin. Initially considered as a nonfunctional peptide, soon after, UAG has been associated to an insulin sensitizing action and to a negative action on energy balance. The aim of this study was to analyze the association between the serum levels of UAG and glucose metabolism parameters in obese women, independently from eventual influenc...