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The knowledge base of Big Tech

Mendonça, Sandro; Silva, Eduardo; Damásio, Bruno

Mendonça, S., Silva, E., & Damásio, B. (2025). The knowledge base of Big Tech: Research as a source of informational leadership by the dominant US digital platforms. Telecommunications Policy, 49(7), Article 102908. https://doi.org/10.1016/j.telpol.2025.102908 --- %ABS1% --- This work was supported by national funds through FCT (Fundação para a Ciência e a Tecnologia), under the project - UIDB/04152/2020 - Cent...


Sickle cell retinopathy in pediatric patients

Rodrigues Alves, Nuno; Barão, Catarina; Barros Silva, Patrícia; Ludovico, Inês; Costa, Lívio; Silva, Eduardo; Anjos, Rita; Serras Pereira, Rita

Purpose: To analyze clinical, laboratory, and Doppler vascular parameters in pediatric sickle cell disease (SCD) patients and identify correlations and predictive factors for sickle cell retinopathy (SCR) and proliferative SCR (PSR). Methods: A retrospective study included pediatric SCD patients screened for SCR between December 2023 and August 2024. Systemic, transcranial-cervical Doppler, and ophthalmologic e...


Developing science and technology

Damásio, Bruno; Mendonça, Sandro; Silva, Eduardo

Damásio, B., Mendonça, S., & Silva, E. M. E. (2023). Developing science and technology: the role of Big Tech. In 32nd European Conference of the International Telecommunications Society (ITS): "Realising the digital decade in the European Union – Easier said than done?", Madrid, Spain, 19th - 20th June 2023 (pp. 1-42). International Telecommunications Society (ITS). https://www.econstor.eu/handle/10419/277951; ...


Menthol-based deep eutectic systems as antimicrobial and anti-inflammatory agen...

Oliveira, Filipe; Silva, Eduardo; Matias, Ana; Silva, Joana M.; Reis, Rui L.; Duarte, Ana Rita C.

PTDC/BBB- 490 EBB/1676/2014. ERC-2016-CoG 725034 (ERC Consolidator Grant Des.solve). Publisher Copyright: © 2022; Effective antimicrobial treatment has been identified as a serious and unmet medical need. Herein, we present a strategy based on deep eutectic systems (DES) to overcome current limitations, answering the need not only to effectively kill bacterial agents but also to avoid their adhesion and prolife...


Optimal design of thedes based on perillyl alcohol and ibuprofen

Silva, Eduardo; Oliveira, Filipe; Silva, Joana M.; Matias, Ana; Reis, Rui L.; Duarte, Ana Rita C.

PTDC/BBB-490 EBB/1676/2014 PTDC/CTM-CTM/29813/2017 SFHR/BD/143902/2019 SFRH/BPD/116779/2016; Therapeutic deep eutectic systems (THEDES) have dramatically expanded their popularity in the pharmaceutical field due to their ability to increase active pharmaceutical ingredients (APIs) bioavailability. However, their biological performance has not yet been carefully scrutinized. Herein, THEDES based on the binary mi...


A closer look in the antimicrobial properties of deep eutectic solvents based o...

Silva, Joana M.; Silva, Eduardo; Reis, Rui L.; Duarte, Ana Rita C.

Foundation for Science and Tech-nology, through project PTDC/BBB- 490 EBB/1676/2014 – Des.Zyme and post-doctoral grant SFRH/BPD/116779/2016. The authors would also like to acknowledge the financial support by ERC-2016-CoG 725034 (ERC Consolidator Grant Des.solve); Microbial infection is a serious and challenging clinical complication that has attracted widespread interest in last decades. In this context, we pr...


A multinodular goiter as the initial presentation of a renal cell carcinoma har...

Bugalho, Maria João; Mendonça, Evelina; Costa, Patrícia; Santos, Jorge Rosa; Silva, Eduardo; Catarino, Ana Luísa; Sobrinho, Luís G

BACKGROUND Secondary involvement of the thyroid gland is rare. Often the origin of the tumor is difficult to identify from the material obtained by fine-needle aspiration cytology. Renal cell carcinoma of the clear-cell type is one of the more common carcinomas to metastasize to the thyroid gland. Somatic mutations of the von Hippel-Lindau tumor suppressor gene are associated with the sporadic form of this tumo...


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