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Sodium alginate/polycaprolactone co-axial wet-spun microfibers modified with N-...
Miranda, Catarina S.; Silva, A. Francisca G.; Seabra, Catarina L.; Reis, Salette; Silva, Maria Manuela; Pereira-Lima, Sílvia M. M. A.In chronic wound (CW) scenarios, Staphylococcus aureus-induced infections are very prevalent. This leads to abnormal inflammatory processes, in which proteolytic enzymes, such as human neutrophil elastase (HNE), become highly expressed. Alanine-Alanine-Proline-Valine (AAPV) is an antimicrobial tetrapeptide capable of suppressing the HNE activity, restoring its expression to standard rates. Here, we proposed the...
Date: 2023
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Origin: RepositóriUM - Universidade do Minho