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Antineoplastic drugs in healthcare settings: Occupational exposure and risk gra...
Portilha-Cunha, MF; Norton, P; Alves, A; Ribeiro, ARL; Silva, AMT; Santos, MSFAntineoplastic drugs (ADs) are hazardous medicinal products highlighted in the EU strategic framework on health and safety at work 2021–2027. To minimize workers' chronic exposure in oncologic settings, regular monitoring programs for these drugs are crucial and mandatory in the EU (Directive 2004/37/EC). No surveillance exists in Portugal, thus we intended to assess environmental contamination and to perform o...
Development and validation of a multicompound LLE–LC–MS/MS method for biomonito...
Portilha-Cunha, MF; Alves, A; Ribeiro, ARL; Silva, AMT; Norton, P; Santos, MSFAntineoplastic drugs are carcinogens, mutagens, or teratogenic substances, which can pose serious risks to professionals. Concerns about chronic exposure to these hazardous medicinal products (HMPs) have led to their prominence in the EU strategic framework on health and safety at work 2021–2027. To estimate and mitigate human exposure to HMPs, regular monitoring programs and, consequently, reliable, sensitive,...
Nanofiltration combined with ozone-based processes for the removal of antineopl...
Gouveia, TIA; Gorito, AM; Cristóvão, MB; Pereira, VJ; Crespo, J; Alves, A; Pereira, MFR; Ribeiro, ARL; Silva, AMT; Santos, MSFOver the past years, there has been an increasing concern about the occurrence of antineoplastic drugs in water bodies. The incomplete removal of these pharmaceuticals from wastewaters has been confirmed by several scientists, making it urgent to find a reliable technique or a combination of techniques capable to produce clean and safe water. In this work, the combination of nanofiltration and ozone (O3)-based ...
An Improved LC-MS/MS Method for the Analysis of Thirteen Cytostatics on Workpla...
Portilha-Cunha, MF; Ramos, S; Silva, AMT; Norton, P; Alves, A; Santos, MSF