3 documents found, page 1 of 1
Improving the Antimycobacterial Drug Clofazimine through Formation of Organic S...
Bento, CM; Silva, AT; Mansano, B; Aguiar, L; Teixeira, C; Gomes, MS; Gomes, P; Silva, T; Ferraz, RThis work reports the synthesis, structural and thermal analysis, and in vitro evaluation of the antimicrobial activity of two new organic salts (OSs) derived from the antimycobacterial drug clofazimine and the fluoroquinolones ofloxacin or norfloxacin. Organic salts derived from active pharmaceutical ingredients (API-OSs), as those herein disclosed, hold promise as cost-effective formulations with improved fea...
Cinnamic acid conjugates in the rescuing and repurposing of classical antimalar...
Silva, AT; Bento, CM; Pena, AC; Figueiredo, LM; Prudêncio, C; Aguiar, L; Silva, T; Ferraz, R; Gomes, MS; Teixeira, C; Gomes, PCinnamic acids are compounds of natural origin that can be found in many different parts of a wide panoply of plants, where they play the most diverse biological roles, often in a conjugated form. For a long time, this has been driving Medicinal Chemists towards the investigation of the therapeutic potential of natural, semi-synthetic, or fully synthetic cinnamic acid conjugates. These efforts have been steadil...
Curso sobre Alergia Alimentar da EAACI
Rosa, S; Alves, R; Piedade, S; Reis, R; Geraldes, L; Figueira Santos, A; Costa, C; Silva, AT; Romeira, AM; Borrego, LM