13 documents found, page 1 of 2

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New contributions to deepen the quality-based safety assessment in the consumpt...

Perestrelo, Rosa; Lopes, Maria da Graça; Silva, Alda Pereira da; Costa, Maria do Céu; Câmara, José S.; Perestrelo, Rosa; Câmara, José

<jats:p>The garden Nasturtium (Tropaeolum majus L.) is increasingly consumed worldwide due to its culinary appeal and perceived health benefits. However, the chemical markers underlying its functional properties remain insufficiently characterized. Building on evidence from a recent human pilot study confirming both high acceptability and dietary safety, we conducted a comprehensive volatilomic and phytochemica...


Nutritional counselling in adults promoting adherence to the Mediterranean diet...

Sousa-Santos, Nuno; Fialho, Mónica; Madeira, Teresa; Clara, Cátia; Veiga, Sofia; Martins, Raquel; Barros, Neuza; Santos, Gabriela; Santos, Osvaldo

Background: Major Depressive Disorder (MDD) is a leading cause of disability worldwide. Approximately one-third of patients with MDD do not respond to treatment, and often exhibit elevated inflammation biomarkers, which are associated with worse prognosis. Previous research has linked healthier dietary patterns, such as the Mediterranean Diet (MedDiet), with a lower risk of MDD and symptoms of depression, poten...


Influence of the TAS2R38 gene single nucleotide polymorphisms in metabolism and...

Mendes Costa, Marta; Silva, Alda Pereira da; Santos, Ana Carolina; Ferreira, Joana; Mascarenhas, Mário Rui; Bicho, Manuel; Barbosa, Ana

The gene TAS2R38 single nucleotide polymorphisms (SNPs-P49A, A262V and V296I) can condition bitter tasting by PAV (proline–alanine–valine) and non-bitter-tasting by AVI (alanine–valine–isoleucine) homozygosity. We evaluated this polymorphisms association with thyroid function, metabolism and anthropometry parameters determined by: Endpoint analysis (SNPs); DXA (fat mass-%, total fat mass—kg, lean mass—kg); Stan...


Nutritional counselling in adults promoting adherence to the Mediterranean diet...

Sousa Santos, Nuno; Fialho, Mónica; Madeira, Teresa; Clara, Cátia; Veiga, Sofia; Martins, Raquel; Barros, Neuza; Santos, Gabriela; Santos, Osvaldo

Background: Major Depressive Disorder (MDD) is a leading cause of disability worldwide. Approximately one-third of patients with MDD do not respond to treatment, and often exhibit elevated inflammation biomarkers, which are associated with worse prognosis. Previous research has linked healthier dietary patterns, such as the Mediterranean Diet (MedDiet), with a lower risk of MDD and symptoms of depression, poten...


Estudo piloto de planta alimentícia não convencional (PANC): adesão da capuchin...

Serrador, Maria da Graça Lopes; Silva, Alda Pereira da; Tavares, Rejane Giacomelli; Rodrigues, Luís Monteiro; Costa, Maria do Céu

As flores de Tropaeolum majus conhecidas como capuchinha, capuchinha de jardim, agrião-da-índia ou agriãomonge são mundialmente utilizadas como suplemento alimentar em dietas à base de plantas, adicionadas a smoothies, sopas, maioneses e saladas por consumidores em busca de fontes de substâncias consideradas benéficas para a saúde humana. A maioria dos estudos mostra qualidades nutricionais e efeitos benéficos ...


Trainees as simulated patients in family medicine/general practice OSCE station...

Ascenção, Raquel; Afonso, David; Lopes, Sandra; Carmo, Pedro; Coelho, Inês; Coelho e Silva, Sara; Gaspar, Catarina; Gonçalves Gaspar, Ivone

In our medical school, an OSCE was recently introduced as a high-stakes exam in the 4th year. For the first time, Family Medicine/General Practice (FM/GP) faculty members were involved in such a complex undertaking, being responsible for two of the ten five-minute stations. Facing limited resources, we decided to invite FM/GP trainees as simulated patients (SP). They were provided with a ninety minute training ...


Association of Aquaporin-3, Aquaporin-7, NOS3 and CYBA polymorphisms with hyper...

da Silva, Inês Vieira; Santos, Ana Carolina; Matos, Andreia; Silva, Alda Pereira da; Soveral, Graça; Rebelo, Irene; Bicho, Manuel

Preeclampsia (PE), a pregnancy disorder influenced by oxidative stress and hypoxia, affects the health of the mother and baby and is associated with an increased risk of future hypertension (HT). Aquaporins are a family of water channels, comprising members that also transport glycerol (aquaglyceroporins) and hydrogen peroxide (peroxiporins), key molecules for metabolic homeostasis and redox signaling. Here, we...


Hypertension and longevity : role of genetic polymorphisms in renin-angiotensin...

Silva, Alda Pereira da; Matos, Andreia; Aguiar, Laura; Marques, Nuno Ramos; Ribeiro, Ricardo; Gil, Ângela; Clara, João Gorjão; Bicho, Manuel

Hypertension (HT), a common age-related disorder, is an important risk factor for cardiovascular disease. This study aims to identify the prevalence of HT in Portuguese centenarians and evaluate whether gene polymorphisms encoding key molecules in blood pressure (BP) regulation are associated with longevity. There were recruited 253 centenarians (100.26 ± 1.98 years) and 268 control subjects (67.51 ± 3.25 years...


The teas of Portuguese centenarians

Silva, Alda Pereira da; Costa, M. Céu; Rijo, Patrícia; Gorjão Clara, João Pedro Pereira; Bicho, Manuel

Introduction: Medicinal plants traditional consumption habits, can contribute to longevity. Methods: A sample of 253 centenarian individuals in Portugal, both sexes, median age 100 years, was studied, to verify past habits in relation to medicinal-interest plants use. It was compared with a control group median age 67 year, with a reduced theoretical probability of reaching 100 years. Results: Among the 8 most ...


Characterization of portuguese centenarian eating habits, nutritional biomarker...

Silva, Alda Pereira da; Valente, A.; Chaves, C.; Matos, A.; Gil, A.; Santos, A. C.; Clara, J. P. Gorjão; Bicho, M.

BACKGROUND AND AIMS: Eating habits may contribute to longevity. We characterized the eating habits and cardiovascular risk (CVR) biomarkers in Portuguese centenarians (CENT) compared to controls. METHODS AND RESULTS: Centenarians (n = 253), 100.26 ± 1.98 years, were compared with 268 controls (67.51 ± 3.25), low (LCR) and high (HCR) CVR (QRISK®2-2016). Anthropometric and body composition were evaluated by bioim...


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