2 documents found, page 1 of 1
Inhibition of enzyme and bacteria activities in diabetic ulcer-like scenarios v...
Ribeiro, Ana R. M.; Miranda, Catarina S.; Silva, Ana Francisca G.; Mendes, Filipa D. P.; Silva, Beatriz M.; Oliveira, Bruna A. S.; Paiva, Eduardo D.In diabetic ulcers, an increased secretion of human neutrophil elastase (HNE) and bacterial infections play crucial roles in hindering healing. Considering that, the present study proposed the development of multi-action polycaprolactone (PCL)/polyethylene glycol (PEG) electrospun fibers incorporating elastase-targeting peptides, AAPV and WAAPV, via blending. Characterization confirmed WAAPV’s efficacy in regul...
Tunable spun fiber constructs in biomedicine: influence of processing parameter...
Miranda, Catarina S.; Silva, Ana Francisca G.; Pereira-Lima, Sílvia M. M. A.; Costa, Susana P. G.; Homem, Natália Cândido; Felgueiras, Helena PradoElectrospinning and wet-spinning have been recognized as two of the most efficient and promising techniques for producing polymeric fibrous constructs for a wide range of applications, including optics, electronics, food industry and biomedical applications. They have gained considerable attention in the past few decades because of their unique features and tunable architectures that can mimic desirable biologi...