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Letter to the Editor Concerning “The Primary Care Research Landscape and its Re...

Oliveira, Eduardo; Silva, Ana João; Amorim, Francisca

N/a.; N/a.

Date: 2022   |   Origin: Acta Médica Portuguesa
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Hypoxia and Macrophages Act in Concert Towards a Beneficial Outcome in Colon Ca...

Martins, Flávia; Oliveira, Rosa; Cavadas, Bruno; Pinto, Filipe; Cardoso, Ana Patrícia; Castro, Flávia; Sousa, Bárbara; Pinto, Marta Laranjeiro

In colon cancer, the prognostic value of macrophages is controversial, and it is still unknown how hypoxia modulates macrophage-cancer cell crosstalk. To unravel this, co-cultures of human primary macrophages and colon cancer cells were performed at 20% and 1% O2, followed by characterization of both cellular components. Different colon cancer patient cohorts were analyzed for hypoxia and immune markers, and th...

Date: 2020   |   Origin: Estudo Geral - Universidade de Coimbra
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