A amendoeira (Prunus dulcis (Mill.) D.A. Webb) é uma espécie com elevada importância económica e social, em Portugal. Em 2020, Portugal continental produziu aproximadamente 32 × 103 toneladas de amêndoa, para uma área de 52340 ha. Embora, atualmente o país apresente condições climáticas favoráveis ao desenvolvimento da espécie, no futuro, os efeitos das alterações climáticas podem alterar os padrões climáticos ...
Accelerated and premature cardiovascular calcification is a hallmark of chronic kidney disease (CKD) patients. Valvular calcification (VC) is a critical indicator of cardiovascular disease and all-cause mortality in this population, lacking validated biomarkers for early diagnosis. Gla-rich protein (GRP) is a cardiovascular calcification inhibitor recently associated with vascular calcification, pulse pressure,...
Accelerated and premature cardiovascular calcification is a hallmark of chronic kidney disease (CKD) patients. Valvular calcification (VC) is a critical indicator of cardiovascular disease and all-cause mortality in this population, lacking validated biomarkers for early diagnosis. Gla-rich protein (GRP) is a cardiovascular calcification inhibitor recently associated with vascular calcification, pulse pressure,...
Monitoring plant phenology has become a widespread methodology to monitor plant behaviour due to the increase, frequency and intensity of extreme climatic events. These extreme climatic events emphasise both plant susceptibility and farmers’ vulnerability, as the latter constantly face the need to change or adjust cultural operations on commercial orchards, since these events have important economic repercussio...
A fenologia estuda a morfologia dos diferentes estados do desenvolvimento das plantas e permite entender e datar o seu desenvolvimento, sendo particularmente importante nas espécies frutícolas, designadamente para o posicionamento das técnicas culturais a realizar ao longo do ciclo anual. Nas prunóideas de clima temperado, nas quais se inclui o pessegueiro, a cerejeira, a ameixeira e a amendoeira, o ciclo anual...
Vascular calcification (VC) is one of the strongest predictors of cardiovascular risk in chronic kidney disease (CKD) patients. New diagnostic/prognostic tools are required for early detection of VC allowing interventional strategies. Gla-rich protein (GRP) is a cardiovascular calcification inhibitor, whose clinical utility is here highlighted. The present study explores, for the first time, correlations betwee...
Worldwide, millions of people are exposed to dietary imbalance that impacts in health and quality of life. In developing countries, like in Brazil, in poor settings, dietary habits, traditionally hypoproteic, are changing rapidly to western-type high-fat foods. These rapidly changing dietary habits are imposing new challenges to human health and there are many questions in the field that remain to be answered. ...
Colorectal cancer is frequently diagnosed at an advanced stage due to the absence of early clinical indicators. Hence, the identification of new targeting molecules is crucial for an early detection and development of targeted therapies. This study aimed to identify and characterize novel peptides specific for the colorectal cancer cell line RKO using a phage-displayed peptide library. After four rounds of sele...
Worldwide, millions of people are exposed to dietary imbalance that impacts in health and quality of life. In developing countries, like in Brazil, in poor settings, dietary habits, traditionally hypoproteic, are changing rapidly to western-type high-fat foods. These rapidly changing dietary habits are imposing new challenges to human health and there are many questions in the field that remain to be answered. ...
Eating and drinking are dynamic processes where both sensations and emotions might evolve or change over time during multiple bites/sips. However, most previous studies have measured food‐evoked emotions statically, that is, at a fixed time point after consumption and using a single bite/sip approach. This study aimed to explore the sensitivity of temporal dominance of sensations (TDS), of emotions (TDE), and t...