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Proteomics characterization of human uterine samples during reproductive ageing

Dias, Bruna; Formoso, Inês; Guedes-Martins, Luís; Almeida, Henrique; Silva, Elisabete; Silva, André M.N.; Matos, Liliana

Nowadays, postponing motherhood has become more common in modern societies. Such decision rises major social and health concerns, as advanced maternal age associates with low fertility, pregnancy complications and a greater need for assisted reproductive techniques. Female reproductive ageing is associated with alterations that are particularly evident in the ovaries. Yet, given the pivotal contribution of the ...


Proteomics Characterization of Human Uterine Samples During Reproductive Ageing

Dias, Bruna; Formoso, Inês; Martins, Luís Guedes; Almeida, Henrique; Silva, Elisabete; Silva, André M.N.; Matos, Liliana


Phytochemical characterization and biological activities of green tea (Camellia...

Barreira, Sérgio; Moutinho, Carla; Silva, André M.N.; Neves, José Manuel Gomes da Silva; Seo, Ean-Jeong; Hegazy, Mohamed-Elamir F.; Efferth, Thomas

Background: Green tea is not only one of the most widely consumed beverages worldwide, but is also known for its health promoting and therapeutic effects. Green tea is cultivated in areas with high humidity and acidic soils in China, Indonesia and Japan. Those places have well-marked dry and rainy seasons. In opposite, Azores have a climate with constant average annual rainfall and, unlike eastern regions, rela...


Phytochemical characterization and biological activities of green tea (Camellia...

Barreira, Sérgio; Moutinho, Carla; Silva, André M.N.; Neves, José Manuel Gomes da Silva; Seo, Ean-Jeong; Hegazy, Mohamed-Elamir F.; Efferth, Thomas

Background: Green tea is not only one of the most widely consumed beverages worldwide, but is also known for its health promoting and therapeutic effects. Green tea is cultivated in areas with high humidity and acidic soils in China, Indonesia and Japan. Those places have well-marked dry and rainy seasons. In opposite, Azores have a climate with constant average annual rainfall and, unlike eastern regions, rela...


Using decellularized human uterine samples to assess the influence of the extra...

Moreira, Mafalda; Silva, André M.N.; Guedes-Martins, Luís; Saraiva, Joaquim; Almeira, Henrique; Silva, Elisabete; Matos, Liliana


New hydrophilic 3-hydroxy-4-pyridinone chelators with ether-derived substituent...

Moniz, Tânia; Cunha-Silva, Luís; Mesquita, Raquel B.R.; Miranda, Joana L.A.; Silva, André M.N.; Silva, Ana M.G.; Rangel, António O.S.S.

Three new hydrophilic 3-hydroxy-4-pyridinone chelators containing ether-derived substituents were prepared by a more sustainable synthetic protocol that involves the use of microwave heating and commercially available amines, allowing the successful production of highly water soluble chelators with improved reaction yields and reaction times. Compared with parent 3-hydroxy-4-pyridinone ligands, the new compound...


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