Oxidative stress and mitochondrial dysfunction have been associated with metabolic and age-related diseases. Thus, the prevention of mitochondrial oxidative damage is nowadays a recognized pharmacological strategy to delay disease progression. Epidemiological studies suggested an association between the consumption of polyphenol-rich diet and the prevention of different pathologies, including diseases with a mi...
Surgical adhesives can be applied to wound closure and to covering and protecting surface wounds. Depending on their degradability, they can then slough off or can be reabsorbed by the organism when the wound initiates the healing process. In this work, we intended to develop a new urethane-based bioadhesive that could accomplish these purposes. Urethanes are considered to be promising candidates as adhesives b...
Surgical adhesives have been used for several applications, including haemostasis, sealing air leakages and tissue adhesion. The aim of this work was to develop a biodegradable urethane-based bioadhesive containing free isocyanate groups. This material presents the advantage of being biodegradable, biocompatible and having the capacity of reacting with amino groups present in the biological molecules.; http://w...