23 documents found, page 1 of 3
Brazilian Society of Hepatology and Brazilian Society of Infectious Diseases Gu...
Ferraz,Maria Lucia; Strauss,Edna; Perez,Renata Mello; Schiavon,Leonardo; Ono,Suzane Kioko; Pessoa,Mario Guimarães; Ferreira,Adalgisa PaivaAbstract Chronic hepatitis B is an important health problem that can progress to cirrhosis and complications such as hepatocellular carcinoma. There is approximately 290 million of people with chronic hepatitis B virus (HBV) infection worldwide, however only 10% of patients are currently identified.Most part of Brazil is considered of low prevalence of HBV infection but there are some regions with higher freque...
Serum levels of immunoglobulin free light chains in patients with chronic hepat...
Oliveira,Isabela S.; Cabral,Milena S.; Jesus,Larissa S.; Paraná,Raymundo; Atta,Ajax M.; Atta,Maria Luiza B. SousaHepatitis C virus (HCV) infects B-lymphocytes, provokes cellular dysfunction and causes lymphoproliferative diseases such as cryoglobulinemia and non-Hodgkin's B-cell lymphoma. In the present study, we investigated the serum levels of kappa and lambda free light chains (FLC) of immunoglobulins and the kappa/lambda FLC ratio in Brazilian patients with chronic HCV infection and cryoglobulinemia. We also analyzed ...
Hepatitis D virus infection in the Western Brazilian Amazon - far from a vanish...
Braga,Wornei Silva Miranda; Castilho,Márcia da Costa; Borges,Fabiane Giovanella; Leão,Jorge Roberto Di Tommaso; Martinho,Ana Cristina de SouzaINTRODUCTION: A decline in hepatitis D virus (HDV) occurrence was described in Europe and Asia. We estimated HDV prevalence in the Brazilian Amazon following hepatitis B vaccination. METHODS: This is a cross-sectional survey of HDV measured by total antibodies to HDV (anti-HD T). RESULTS: HDV prevalence was 41.9% whiting HBsAg carries and was associated with age (PR = 1.96; 95% CI 1.12-3.42; p = 0.01), hepatiti...
Smooth muscle antibodies and cryoglobulinemia are associated with advanced live...
Andrade,Luis Jesuino de Oliveira; Melo,Paulo Roberto Santana de; Atta,Ajax Mercês; Atta,Maria Luiza Brito de Sousa; Jesus,Larissa Santana deCryoglobulinemia and non-organ-specific-autoantibody are biomarkers of autoimmunity of the chronic infection caused by hepatitis C virus (HCV). In this work, we report the association between the presence of smooth muscle antibodies (SMA) and cryoglobulinemia and chronic liver disease in HCV carriers. Sixty-five untreated HCV patients, 38 women and 27 men were included in this study. Cryoglobulinemia was tested...
Impact of psychiatric disorders on the quality of life of brazilian HCV-infecte...
Batista-Neves,Susana; Quarantini,Lucas C.; Galvão-de Almeida,Amanda; Cardeal,Maurício; Lacerda,Acioly L.; Paraná,Raymundo; Reis de-Oliveira,IrismarThe aim of our study was to determine the impact of psychiatric comorbidities on the health-related quality of life of HCV-infected patients. Assessment of clinical, socio-demographic and quality of life data of the patients followed up at a Hepatology unit was performed by using a standard questionnaire and the SF-36 instrument. Psychiatric diagnoses were confirmed by using the Mini International Neuropsychiat...
Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha an...
Andrade,Luis Jesuíno de Oliveira; Atta,Ajax Mercês; D'Almeida Junior,Argemiro; Paraná,RaymundoHepatitis C (HCV) is now the main cause of chronic hepatic disease, cirrhosis and hepatocellular carcinoma. Several extrahepatic diseases have been associated with chronic HCV infection, and in most cases appear to be directly related to the viral infection. Thyroid disorders are common in patients with chronic HCV. Some patients with chronic hepatitis C experience thyroid problems, and thyroid dysfunction may ...
Hepatotropic viruses in the Brazilian Amazon: a health threat
Paraná,Raymundo; Vitvitski,Ludmila; Pereira,Joao EduardoViral Hepatitis B, C and D are a serious public health problem in Brazil and other South American countries, mainly in the Amazonian region. Despite the paucity of clinical and epidemiological studies, a high prevalence of Hepatitis viruses has often been described in this area. Genotype F of Hepatitis B and Genotype III of Hepatitis D have been found to be quite prevalent in this area and preliminary studies h...
Occult B infection in the Brazilian northeastern region: a preliminary report
Almeida,Delvone; Tavares-Neto,José; Trepo,Christian; Almeida,Alessandro; Mello,Caroline; Chemin,Isabelle; Paraná,RaymundoA sentinel study on viral hepatitis is currently being carried out in the village of Cavunge in a semiarid rural region of the state of Bahia, northeastern Brazil. This study has identified individuals in whom anti-HBc IgG was the only serological marker for hepatitis B virus (HBV). This serological pattern may constitute evidence of occult HBV infection. This study Investigated the possibility of occult hepati...
Características da reação tipo 1 e associação com vírus B e C da hepatite na ha...
Rego,Vitória P.A.; Machado,Paulo R.L.; Martins,Isabela; Trindade,Ronald; Paraná,RaymundoO episódio reacional tipo 1 ou reação reversa é ocorrência inflamatória aguda que atinge a pele e nervos periféricos, encontrada em até 30% dos pacientes com hanseníase, sendo causa comum de incapacidade física. Fatores de risco associados incluem uso de poliquimioterapia e infecções virais. Neste estudo, foram avaliados 620 pacientes com hanseníase. Reação reversa foi diagnosticada em 121 (19,5%) casos, sendo ...
Chronic hepatitis C and fibrosis: evidences for possible estrogen benefits
Codes,Liana; Matos,Ludmilla; Paraná,RaymundoThe main injury caused by hepatitis C virus is the hepatic fibrosis, as a result of a chronic inflammatory process in the liver characterized by the deposit of components from the extracellular matrix. The fibrosis development leads to the modification of the hepatic architecture, of the hepatocellular function and to irregularities in the microcirculation. The tissue remodeling process observed in fibrosis has...